Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302.
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Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancerAnticancer efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in osteolytic breast cancer murine models.Temperature induces significant changes in both glycolytic reserve and mitochondrial spare respiratory capacity in colorectal cancer cell lines.Hypoxia Imaging With PET Correlates With Antitumor Activity of the Hypoxia-Activated Prodrug Evofosfamide (TH-302) in Rodent Glioma Models.Radiotherapy Synergizes with the Hypoxia-Activated Prodrug Evofosfamide: In Vitro and In Vivo Studies.Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.Pulsed Electron Paramagnetic Resonance Imaging: Applications in the Studies of Tumor Physiology.Contribution of Harold M. Swartz to In Vivo EPR and EPR Dosimetry.
P2860
Q34756921-C94311E8-02EB-48DF-B68A-9936FAF2B697Q36706902-B929156D-6130-4B5D-8051-6721B2F2CF0EQ38710513-9FC61BD4-187A-405D-A4DC-09BA579DD5AAQ41467964-7987E6ED-A1B3-44FC-BE3E-12D0F930DD93Q46018609-F459E2C5-D46D-42BA-99EA-562DFFA6F722Q47615969-410CCB5B-D64B-4B92-859E-842F9ADC0C26Q47843870-BC560BD6-2431-40E4-85E6-596645329072Q48281913-8A7A582C-D872-4CD4-9325-7F228D640638
P2860
Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@ast
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@en
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@nl
type
label
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@ast
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@en
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@nl
prefLabel
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@ast
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@en
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@nl
P2093
P2860
P50
P1433
P1476
Pyruvate induces transient tum ...... oxia-activated prodrug TH-302.
@en
P2093
Aparna H Kesarwala
James B Mitchell
Jeeva P Munasinghe
Jonathan W Wojtkowiak
Keita Saito
Masayuki Matsuo
Murali C Krishna
Nallathamby Devasahayam
Rajani Choudhuri
Sankaran Subramanian
P2860
P304
P356
10.1371/JOURNAL.PONE.0107995
P407
P577
2014-09-25T00:00:00Z