about
Heterogeneous nucleation of protein crystals on fluorinated layered silicateCamptothecin binds to a synthetic peptide identified by a T7 phage display screen.Synthesis of a biotinylated camptothecin derivative and determination of the binding sequence by T7 phage display technology.Identification of C10 biotinylated camptothecin (CPT-10-B) binding peptides using T7 phage display screen on a QCM device.Identification of a methotrexate-binding peptide from a T7 phage display screen using a QCM device.Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool.Identification of trimannoside-recognizing peptide sequences from a T7 phage display screen using a QCM device.Identification of small molecule binding molecules by affinity purification using a specific ligand immobilized on PEGA resin.A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit.A screening of a library of T7 phage-displayed peptide identifies E2F-4 as an etoposide-binding protein.Screening of a library of T7 phage-displayed peptides identifies alphaC helix in 14-3-3 protein as a CBP501-binding site.Camptothecin (CPT) directly binds to human heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and inhibits the hnRNP A1/topoisomerase I interaction.In vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization.Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302.Identification and characterization of the direct interaction between methotrexate (MTX) and high-mobility group box 1 (HMGB1) protein.Ridaifen G, tamoxifen analog, is a potent anticancer drug working through a combinatorial association with multiple cellular factors.Ridaifen B, a tamoxifen derivative, directly binds to Grb10 interacting GYF protein 2.Design of a 15N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State.Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases.Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction.Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized (13) C-Labeled Molecular Probe.A Strategy to Design Hyperpolarized 13 C Magnetic Resonance Probes Using [1-13 C]α-Amino Acid as a Scaffold Structure.Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity.Effect of ionic interaction between a hyperpolarized magnetic resonance chemical probe and a gadolinium contrast agent for the hyperpolarized lifetime after dissolution.Design of a hyperpolarized (15)N NMR probe that induces a large chemical-shift change upon binding of calcium ions.DNA polymerase mu interacts with a meiosis-specific RecA homolog Lim15 during meiosis in Coprinus cinereus.Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reactionUse of layer silicate for protein crystallization: effects of Micromica and chlorite powders in hanging dropsLariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171Characterization of marine X-family DNA polymerases and comparative analysis of base excision repair proteinsFoam fractionation of protein: correlation of protein adsorption onto bubbles with a pH-induced conformational transition13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Yoichi Takakusagi
@ast
Yoichi Takakusagi
@en
Yoichi Takakusagi
@es
Yoichi Takakusagi
@nl
Yoichi Takakusagi
@sl
type
label
Yoichi Takakusagi
@ast
Yoichi Takakusagi
@en
Yoichi Takakusagi
@es
Yoichi Takakusagi
@nl
Yoichi Takakusagi
@sl
prefLabel
Yoichi Takakusagi
@ast
Yoichi Takakusagi
@en
Yoichi Takakusagi
@es
Yoichi Takakusagi
@nl
Yoichi Takakusagi
@sl
P106
P1153
8947189900
P31
P496
0000-0002-6786-0748