Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor - Wikidata - wikimedia - TriplyDB

Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor

Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor

http://www.wikidata.org/entity/Q34267718

about

Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor Targeting the hepatocyte growth factor-cMET axis in cancer therapy Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist Structural basis for agonism and antagonism of hepatocyte growth factor Crystal structure of an engineered YopM-InlB hybrid protein Analysis of progress and challenges for various patterns of c-MET-targeted molecular imaging: a systematic review.Yhhu3813 is a novel selective inhibitor of c-Met kinase that inhibits c-Met-dependent neoplastic phenotypes of human cancer cells Engineering hepatocyte growth factor fragments with high stability and activity as Met receptor agonists and antagonists.The Hepatocyte Growth Factor Receptor: Structure, Function and Pharmacological Targeting in Cancer A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.Structural basis of hepatocyte growth factor/scatter factor and MET signalling.Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells Hepatocyte growth factor signaling in intrapancreatic ductal cells drives pancreatic morphogenesis HGF and MET mutations in primary and secondary lymphedema Role of HGF/MET axis in resistance of lung cancer to contemporary management.Receptor tyrosine kinases and the regulation of macrophage activation.To move or not to move? Semaphorin signalling in cell migration.Retrospective Review of MET Gene Mutations.Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma Genetic profiles of cervical tumors by high-throughput sequencing for personalized medical care.Direct binding of hepatocyte growth factor and vascular endothelial growth factor to CD44v6.High-throughput mutational analysis of the human cancer genome.Targeting the HGF-cMET Axis in Hepatocellular Carcinoma.A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors.Plexin B1 suppresses c-Met in melanoma: a role for plexin B1 as a tumor-suppressor protein through regulation of c-Met.Targeting the HGF/Met signaling pathway in cancer therapy Mechanism of Fas signaling regulation by human herpesvirus 8 K1 oncoprotein Critical signal transduction pathways in CLL.MET targeted therapy for lung cancer: clinical development and future directions Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.Paradoxical action of growth factors: antiproliferative and proapoptotic signaling by HGF/c-MET.Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase.The binding properties of minimal oligosaccharides reveal a common heparan sulfate/dermatan sulfate-binding site in hepatocyte growth factor/scatter factor that can accommodate a wide variety of sulfation patterns.cMET in NSCLC: Can We Cut off the Head of the Hydra? From the Pathway to the Resistance.HGF/c-met system targeting PI3K/AKT and STAT3/phosphorylated-STAT3 pathways in pituitary adenomas: an immunohistochemical characterization in view of targeted therapies.Hepatocyte growth factor and alternative splice variants - expression, regulation and implications in osteogenesis and bone health and repair Targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges.

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Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor

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2003 nî lūn-bûn

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Functional map and domain stru ...... e growth factor/scatter factor

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Proceedings of the National Academy of Sciences of the United States of America

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Functional map and domain stru ...... e growth factor/scatter factor

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Abhishek Bandyopadhyay

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Ermanno Gherardi

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Guido Hartmann

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Mark E Youles

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P Jonathan G Butler

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Ricardo N Miguel

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P2860

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

Crystal structure of the extracellular segment of integrin alpha Vbeta3

Molecular cloning and expression of human hepatocyte growth factor

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

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