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Insights from the sea: structural biology of marine polyketide synthases

Insights from the sea: structural biology of marine polyketide synthases

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Structural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic Pathways Architecture of the polyketide synthase module: surprises from electron cryo-microscopy Natural products: a continuing source of novel drug leads Modeling linear and cyclic PKS intermediates through atom replacement.In Vitro Reconstitution of Metabolic Pathways: Insights into Nature's Chemical Logic.Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase The psymberin story--biological properties and approaches towards total and analogue syntheses.Unique marine derived cyanobacterial biosynthetic genes for chemical diversity.Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis.Molecular Genetic Characterization of an Anthrabenzoxocinones Gene Cluster in Streptomyces Sp. FJS31-2 for the Biosynthesis of BE-24566B and Zunyimycin Ale.PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production.

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Insights from the sea: structural biology of marine polyketide synthases

http://www.wikidata.org/entity/Q34267983

description

2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Insights from the sea: structural biology of marine polyketide synthases

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Insights from the sea: structural biology of marine polyketide synthases

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Insights from the sea: structural biology of marine polyketide synthases

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Insights from the sea: structural biology of marine polyketide synthases

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Insights from the sea: structural biology of marine polyketide synthases

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Insights from the sea: structural biology of marine polyketide synthases

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Insights from the sea: structural biology of marine polyketide synthases

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Insights from the sea: structural biology of marine polyketide synthases

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Insights from the sea: structural biology of marine polyketide synthases

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Natural Product Reports

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Insights from the sea: structural biology of marine polyketide synthases

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David L Akey

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Dheeraj Khare

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Janet L Smith

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Jennifer J Gehret

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P2860

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteria

Discovery and characterization of a marine bacterial SAM-dependent chlorinase

Lessons from the past and charting the future of marine natural products drug discovery and chemical biology

Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel

Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE

Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases

Crystal structure and mechanism of a bacterial fluorinating enzyme

Structural and Mechanistic Analysis of Protein Interactions in Module 3 of the 6-Deoxyerythronolide B Synthase

Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching

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1038-1049

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scholarly article

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10.1039/C2NP20016C

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10

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29

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3709256

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