An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers.
about
Exploring the effects of polymorphisms on cis-regulatory signal transduction responseEvidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in miceFrom mice to humans.Dissecting the causal genetic mechanisms of coronary heart disease.Living long and ageing well: is epigenomics the missing link between nature and nurture?How does the Mediterranean diet promote cardiovascular health? Current progress toward molecular mechanisms: gene-diet interactions at the genomic, transcriptomic, and epigenomic levels provide novel insights into new mechanisms.In vitro scan for enhancers at the TCF7L2 locus.Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.Redundant enhancers and causal variants in the TCF7L2 gene.A genetic risk score that includes common type 2 diabetes risk variants is associated with gestational diabetes.
P2860
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P2860
An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers.
description
2012 nî lūn-bûn
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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@ast
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@en
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@nl
type
label
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@ast
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@en
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@nl
prefLabel
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@ast
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@en
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@nl
P2860
P1433
P1476
An in vivo cis-regulatory scre ...... ple tissue-specific enhancers.
@en
P2093
Graeme I Bell
Marcelo A Nobrega
P2860
P304
P356
10.1371/JOURNAL.PONE.0036501
P407
P50
P577
2012-05-10T00:00:00Z