Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
about
New Insights into Wnt-Lrp5/6-β-Catenin Signaling in MechanotransductionProstaglandin E2 signals through PTGER2 to regulate sclerostin expressionLrp5 functions in bone to regulate bone massWnts talking with the TGF-β superfamily: WISPers about modulation of osteoarthritisWNT signaling in bone development and homeostasisLRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxinWnt signaling in bone and muscleLRP5 and LRP6 in development and diseaseRapid phenotyping of knockout mice to identify genetic determinants of bone strengthWNT signaling in bone homeostasis and disease: from human mutations to treatmentsRegulation of Wnt/β-catenin signaling within and from osteocytesWhere Wnts went: the exploding field of Lrp5 and Lrp6 signaling in boneFrom estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosisDissecting molecular differences between Wnt coreceptors LRP5 and LRP6The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineageThe Wnt co-receptor Lrp6 is required for normal mouse mammary gland developmentGenetic evidence that SOST inhibits WNT signaling in the limbWnt11 promotes osteoblast maturation and mineralization through R-spondin 2The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesisInhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisitionPTH stimulates bone formation in mice deficient in Lrp5Macrophage Wnt7b is critical for kidney repair and regenerationEssential role of beta-catenin in postnatal bone acquisitionRegulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor.Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formationDigit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice.The effect of LRP5 polymorphisms on bone mineral density is apparent in childhood.Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific mannerWise regulates bone deposition through genetic interactions with Lrp5Mechanisms of aortic valve calcification: the LDL-density-radius theory: a translation from cell signaling to physiology.Mutations in TSPAN12 cause autosomal-dominant familial exudative vitreoretinopathy.TIEG1 modulates β-catenin sub-cellular localization and enhances Wnt signaling in bone.Novel links among Wnt and TGF-beta signaling and Runx2.LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy.Bone mass is inversely proportional to Dkk1 levels in mice.Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice.Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouseTargeting the LRP5 pathway improves bone properties in a mouse model of osteogenesis imperfecta.Clinical and molecular findings in osteoporosis-pseudoglioma syndrome.
P2860
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P2860
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/01)
@nl
наукова стаття, опублікована в грудні 2004
@uk
مقالة علمية (نشرت في ديسمبر 2004)
@ar
name
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@ast
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@en
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@nl
type
label
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@ast
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@en
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@nl
prefLabel
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@ast
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@en
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@nl
P2093
P2860
P3181
P356
P1476
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
@en
P2093
Bart O. Williams
Bree D. Buckner-Berghuis
Cassandra R. Zylstra
J. Fred Hess
James H. Resau
Matthew L. Warman
Minrong Ai
Sheri L. Holmen
Troy A. Giambernardi
Vaida Glatt
P2860
P304
P3181
P356
10.1359/JBMR.040907
P577
2004-12-01T00:00:00Z