Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes.
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Antibody responses to envelope glycoproteins in HIV-1 infectionHIV-1 neutralizing antibodies: understanding nature's pathwaysVirological features associated with the development of broadly neutralizing antibodies to HIV-1Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 InfectionDevelopmental pathway for potent V1V2-directed HIV-neutralizing antibodiesStructures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine designDeconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and ImmunityStructure-Based Reverse Vaccinology Failed in the Case of HIV Because it Disregarded Accepted Immunological TheoryHuman antibodies that neutralize HIV-1: identification, structures, and B cell ontogeniesWhat Are the Most Powerful Immunogen Design Vaccine Strategies?Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation.Autoreactivity in HIV-1 broadly neutralizing antibodies: implications for their function and induction by vaccination.The stem of vesicular stomatitis virus G can be replaced with the HIV-1 Env membrane-proximal external region without loss of G function or membrane-proximal external region antigenic properties.Onset of immune senescence defined by unbiased pyrosequencing of human immunoglobulin mRNA repertoires.Human germline antibody gene segments encode polyspecific antibodies.B-cell repertoire responses to varicella-zoster vaccination in human identical twinsAntibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.Tissue-specific expressed antibody variable gene repertoiresAnalysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunizationHoning a harder-hitting hammerhead improves broadly neutralizing antibody breadth and potencyAutopolyreactivity Confers a Holistic Role in the Immune System.Competitive exclusion by autologous antibodies can prevent broad HIV-1 antibodies from arising.High-quality full-length immunoglobulin profiling with unique molecular barcoding.Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodiesBoosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization.Delineation of autoantibody repertoire through differential proteogenomics in hepatitis C virus-induced cryoglobulinemia.Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose PatchDe novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts.Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding.Ontogeny-based immunogens for the induction of V2-directed HIV broadly neutralizing antibodies.Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization.HIV vaccine research and discovery in the nonhuman primates model: a unified theory in acquisition prevention and control of SIV infectionImpact of new sequencing technologies on studies of the human B cell repertoire.Profiling the IgOme: meeting the challenge.Immunologic Basis for Long HCDR3s in Broadly Neutralizing Antibodies Against HIV-1.Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies.
P2860
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P2860
Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Human peripheral blood antibod ...... ited subset of germline genes.
@ast
Human peripheral blood antibod ...... ited subset of germline genes.
@en
Human peripheral blood antibod ...... ited subset of germline genes.
@nl
type
label
Human peripheral blood antibod ...... ited subset of germline genes.
@ast
Human peripheral blood antibod ...... ited subset of germline genes.
@en
Human peripheral blood antibod ...... ited subset of germline genes.
@nl
prefLabel
Human peripheral blood antibod ...... ited subset of germline genes.
@ast
Human peripheral blood antibod ...... ited subset of germline genes.
@en
Human peripheral blood antibod ...... ited subset of germline genes.
@nl
P2860
P1433
P1476
Human peripheral blood antibod ...... ited subset of germline genes.
@en
P2093
Bryan S Briney
Jordan R Willis
P2860
P304
P356
10.1371/JOURNAL.PONE.0036750
P407
P577
2012-05-09T00:00:00Z