De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts.
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The evolution within usHIV broadly neutralizing antibody targetsStructural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 DonorsHigh-Throughput Sequencing-Based Immune Repertoire Study during Infectious DiseaseAccurate and predictive antibody repertoire profiling by molecular amplification fingerprintingPractical guidelines for B-cell receptor repertoire sequencing analysisComputational tools for epitope vaccine design and evaluationClonify: unseeded antibody lineage assignment from next-generation sequencing dataThe promise and challenge of high-throughput sequencing of the antibody repertoire.The Antibody Germline/Maturation Hypothesis, Elicitation of Broadly Neutralizing Antibodies Against HIV-1 and Cord Blood IgM RepertoiresAnalysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunizationRhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis.Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing Data.Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese DonorToward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding.Selection of therapeutic H5N1 monoclonal antibodies following IgVH repertoire analysis in mice.Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAsSONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts.Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors.Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers.Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization.Rare, high-affinity anti-pathogen antibodies from human repertoires, discovered using microfluidics and molecular genomics.Study of antibody repertoires to the CD4 binding site of gp120 of a Chinese HIV-1-infected elite neutralizer, using 454 sequencing and single-cell sorting.Identification and specificity of broadly neutralizing antibodies against HIVHidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer.Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants.Next-generation approaches to advancing eco-immunogenomic research in critically endangered primates.Sequence analysis of feline immunoglobulin mRNAs and the development of a felinized monoclonal antibody specific to feline panleukopenia virus.Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CAIntegrating high-throughput screening and sequencing for monoclonal antibody discovery and engineering.In-Depth Analysis of Human Neonatal and Adult IgM Antibody Repertoires.5' Rapid Amplification of cDNA Ends and Illumina MiSeq Reveals B Cell Receptor Features in Healthy Adults, Adults With Chronic HIV-1 Infection, Cord Blood, and Humanized Mice.VDJServer: A Cloud-Based Analysis Portal and Data Commons for Immune Repertoire Sequences and Rearrangements.A Comprehensive Analysis of the T and B Lymphocytes Repertoire Shaped by HIV Vaccines
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P2860
De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
De novo identification of VRC0 ...... uencing of B-cell transcripts.
@en
De novo identification of VRC0 ...... uencing of B-cell transcripts.
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type
label
De novo identification of VRC0 ...... uencing of B-cell transcripts.
@en
De novo identification of VRC0 ...... uencing of B-cell transcripts.
@nl
prefLabel
De novo identification of VRC0 ...... uencing of B-cell transcripts.
@en
De novo identification of VRC0 ...... uencing of B-cell transcripts.
@nl
P2093
P2860
P50
P356
P1476
De novo identification of VRC0 ...... uencing of B-cell transcripts.
@en
P2093
Baoshan Zhang
Joseph P Casazza
Krisha McKee
Lawrence Shapiro
Peter D Kwong
Sijy O'Dell
Xueling Wu
P2860
P304
P356
10.1073/PNAS.1306262110
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P577
2013-10-08T00:00:00Z