CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. - Wikidata - wikimedia - TriplyDB

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

http://www.wikidata.org/entity/Q34275804

about

HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion molecules Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1 Non-transcriptional interactions of Hox proteins: inventory, facts, and future directions Role of HOXA9 in leukemia: dysregulation, cofactors and essential targets Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B NUP98 dysregulation in myeloid leukemogenesis CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis Cul4A is required for hematopoietic stem-cell engraftment and self-renewal Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.A novel lncRNA uc.134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1.Nedd8 on cullin: building an expressway to protein destruction.Improved ex vivo expansion of adult hematopoietic stem cells by overcoming CUL4-mediated degradation of HOXB4.Cullins and cancer.ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential.Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome TGFbeta/BMP inhibits the bone marrow transformation capability of Hoxa9 by repressing its DNA-binding ability.Hoxa9 transduction induces hematopoietic stem and progenitor cell activity through direct down-regulation of geminin protein HoxA10 influences protein ubiquitination by activating transcription of ARIH2, the gene encoding Triad1.Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1.HOXA9 participates in the transcriptional activation of E-selectin in endothelial cells.Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation.Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.Control of self-renewal and differentiation of hematopoietic stem cells: HOXB4 on the threshold.Ubiquitylation in normal and malignant hematopoiesis: novel therapeutic targets.Proliferation defects and genome instability in cells lacking Cul4A.Morpholino-mediated knockdown in primary chondrocytes implicates Hoxc8 in regulation of cell cycle progression.CRL4s: the CUL4-RING E3 ubiquitin ligases.CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1.CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity.Recombinant TAT-BMI-1 fusion protein induces ex vivo expansion of human umbilical cord blood-derived hematopoietic stem cells.Identification of a tumor suppressor network in T-cell leukemia.

P2860

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P2860

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

http://www.wikidata.org/entity/Q34275804

description

2003 nî lūn-bûn

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2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@ast

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@en

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@nl

type

label

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@ast

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@en

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@nl

prefLabel

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@ast

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@en

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@nl

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P1433

The EMBO Journal

P1476

CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.

@en

P2093

Giovanni Morrone

http://www.w3.org/2001/XMLSchema#string

Jianxuan Zhang

http://www.w3.org/2001/XMLSchema#string

Liang Ma

http://www.w3.org/2001/XMLSchema#string

Malcolm Moore

http://www.w3.org/2001/XMLSchema#string

Pengbo Zhou

http://www.w3.org/2001/XMLSchema#string

Xiaoai Chen

http://www.w3.org/2001/XMLSchema#string

Xiaoling Lu

http://www.w3.org/2001/XMLSchema#string

Yue Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1

Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells

The ubiquitin system

A system for stable expression of short interfering RNAs in mammalian cells

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

Homeobox genes and axial patterning

Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes

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6057-6067

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scholarly article

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10.1093/EMBOJ/CDG577

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22

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22

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2003-11-01T00:00:00Z

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9015534

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14609952

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275435

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