p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients - Wikidata - wikimedia - TriplyDB

p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

http://www.wikidata.org/entity/Q34276605

about

Group I and II mammalian PAKs have different modes of activation by Cdc42 Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer Targeting Cdc42 in cancer PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?Signaling, Regulation, and Specificity of the Type II p21-activated Kinases Design, synthesis and biological evaluation of 1-phenanthryl-tetrahydroisoquinoline derivatives as novel p21-activated kinase 4 (PAK4) inhibitors microRNA-126 suppresses PAK4 expression in ovarian cancer SKOV3 cells p21-Activated kinase 4 promotes prostate cancer progression through CREB p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells GL-1196 Suppresses the Proliferation and Invasion of Gastric Cancer Cells via Targeting PAK4 and Inhibiting PAK4-Mediated Signaling Pathways P21-activated kinase 4 regulates the cyclin-dependent kinase inhibitor p57(kip2) in human breast cancer PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions.Activated-PAK4 predicts worse prognosis in breast cancer and promotes tumorigenesis through activation of PI3K/AKT signaling.Interplay of PKA and Rac: fine-tuning of Rac localization and signaling.P21-activated kinase 4 involves TSH induced papillary thyroid cancer cell proliferation.p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes.Changes in the transcriptional profile in response to overexpression of the osteopontin-c splice isoform in ovarian (OvCar-3) and prostate (PC-3) cancer cell lines.LC-0882 targets PAK4 and inhibits PAK4-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells.p21-Activated Kinase 4 Promotes Intimal Hyperplasia and Vascular Smooth Muscle Cells Proliferation during Superficial Femoral Artery Restenosis after Angioplasty.The blood-follicle barrier (BFB) in disease and in ovarian function.Discovery of multi-dimensional modules by integrative analysis of cancer genomic data.Applications of RNA interference high-throughput screening technology in cancer biology and virology P21-activated kinase 4 overexpression in metastatic gastric cancer patients Overexpression of P21-activated kinase 4 is associated with poor prognosis in non-small cell lung cancer and promotes migration and invasion.The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.p21-Activated Kinases 1, 2 and 4 in Endometrial Cancers: Effects on Clinical Outcomes and Cell Proliferation.PAK4 confers the malignance of cervical cancers and contributes to the cisplatin-resistance in cervical cancer cells via PI3K/AKT pathway.Paradoxical impact of two folate receptors, FRα and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome.Src, p130Cas, and Mechanotransduction in Cancer Cells Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma Reciprocal regulation of PKA and Rac signaling.Prognostic impact of tumor infiltrating CD8+ T cells in association with cell proliferation in ovarian cancer patients--a study of the OVCAD consortium The Role of Ect2 Nuclear RhoGEF Activity in Ovarian Cancer Cell Transformation.The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells.Genetic control of specificity to steroid-triggered responses in Drosophila.

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p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

http://www.wikidata.org/entity/Q34276605

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@ast

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@en

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@nl

type

label

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@ast

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@en

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@nl

prefLabel

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@ast

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@en

p21-activated kinase 4 regulat ...... to poor prognosis in patients

@nl

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PNAS.0907481107

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Proceedings of the National Academy of Sciences of the United States of America

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p21-activated kinase 4 regulat ...... to poor prognosis in patients

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P2093

Daniel S H Kong

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Esther S Y Wong

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Hoi Yan Chan

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Hongquan Zhang

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Kar Fai Tam

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Michelle K Y Siu

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Oscar G W Wong

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Queeny K Y Chan

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Sai Wah Tsao

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Zhilun Li

http://www.w3.org/2001/XMLSchema#string

P2860

Nucleolar proteome dynamics

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

Src family kinases in tumor progression and metastasis

Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties

P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration

The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins

Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

PAK4 is activated via PI3K in HGF-stimulated epithelial cells

Activated PAK4 regulates cell adhesion and anchorage-independent growth

Nuclear localization and chromatin targets of p21-activated kinase 1

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43

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107

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Staffan Strömblad

Hextan Y S Ngan

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2010-10-06T00:00:00Z

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47357568

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20926745

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