Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
about
Proteasomal degradation of the multifunctional regulator YB-1 is mediated by an F-Box protein induced during programmed cell deathCooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signalingSilencing of KIF14 interferes with cell cycle progression and cytokinesis by blocking the p27(Kip1) ubiquitination pathway in hepatocellular carcinomaFBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cellsCharacterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesiclesPhosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phaseDynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasmMultiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5.The Importance of Ubiquitination and Deubiquitination in Cellular ReprogrammingProtein degradation and the stress responsePhosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed selfThe F-box protein Met30 is required for multiple steps in the budding yeast cell cycle.The PfNF-YB transcription factor is a downstream target of melatonin and cAMP signalling in the human malaria parasite Plasmodium falciparumDirect association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-CThe SCF ubiquitin ligase: insights into a molecular machineTuberin binds p27 and negatively regulates its interaction with the SCF component Skp2Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremorAn acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymesGatifloxacin induces S and G2-phase cell cycle arrest in pancreatic cancer cells via p21/p27/p53Demonstration of ubiquitin thiolester formation of UBE2Q2 (UBCi), a novel ubiquitin-conjugating enzyme with implantation site-specific expressionSignaling from the secretory granule to the nucleus: Uhmk1 and PAMUSP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1The mouse polyubiquitin gene Ubb is essential for meiotic progressionCul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesisA proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cellsSpindle poisons and cell fate: a tale of two pathways.The human ubiquitin conjugating enzyme, UBE2E3, is required for proliferation of retinal pigment epithelial cells.Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy.The reversibility of mitotic exit in vertebrate cells.Gene pleiotropy constrains gene expression changes in fish adapted to different thermal conditions.Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest.Role of proteasomes in disease.Convergence of the 26S proteasome and the REVOLUTA pathways in regulating inflorescence and floral meristem functions in Arabidopsis.The aggregation and inheritance of damaged proteins determines cell fate during mitosis.An ultra-high throughput cell-based screen for wee1 degradation inhibitorsActivation domain-dependent degradation of somatic Wee1 kinaseHyperglycemia impairs proteasome function by methylglyoxalMetabolic control of G1-S transition: cyclin E degradation by p53-induced activation of the ubiquitin-proteasome systemRegulation of ROMK (Kir1.1) channels: new mechanisms and aspects.
P2860
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P2860
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@ast
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@en
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@nl
type
label
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@ast
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@en
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@nl
prefLabel
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@ast
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@en
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@nl
P356
P1476
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover.
@en
P2093
Steven I Reed
P2888
P304
P356
10.1038/NRM1246
P577
2003-11-01T00:00:00Z
P5875
P6179
1004970299