Secretase targets for Alzheimer's disease: identification and therapeutic potential.
about
Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activitiesInvestigation of the noncovalent interactions between anti-amyloid agents and amyloid beta peptides by ESI-MS.Inhibition of amyloid precursor protein processing by beta-secretase through site-directed antibodies.Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate.Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers.Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?Potential novel targets for Alzheimer pharmacotherapy: I. Secretases.Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study.The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism.The systemic amyloidoses: clearer understanding of the molecular mechanisms offers hope for more effective therapies.Protein flexibility in virtual screening: the BACE-1 case studyCombining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments.Nano-biosensors to detect beta-amyloid for Alzheimer's disease management.Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40Ddi1-like protein from Leishmania major is an active aspartyl proteinase.The sulfamide motif in the design of enzyme inhibitors.Differential effects of inhibitors on the gamma-secretase complex. Mechanistic implications.Retrospective molecular docking study of WY-25105 ligand to β-secretase and bias of the three-dimensional structure flexibility.Protective effect of Bajijiasu against β-amyloid-induced neurotoxicity in PC12 cells.Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.
P2860
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P2860
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@ast
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@en
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@nl
type
label
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@ast
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@en
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@nl
prefLabel
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@ast
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@en
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@nl
P356
P1476
Secretase targets for Alzheimer's disease: identification and therapeutic potential.
@en
P2093
P304
P356
10.1021/JM0004897
P407
P577
2001-06-01T00:00:00Z