Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts
about
Live cell division dynamics monitoring in 3D large spheroid tumor models using light sheet microscopy.PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture.FAM83A confers EGFR-TKI resistance in breast cancer cells and in miceMammary-derived growth inhibitor (MDGI) interacts with integrin α-subunits and suppresses integrin activity and invasionp140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activityThe hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cellsAdhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin.Ionizing radiation induces heritable disruption of epithelial cell interactionsBreast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-cultureMicroRNAs as diagnostic and prognostic biomarkers in colorectal cancerNormal morphogenesis of epithelial tissues and progression of epithelial tumors.Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary glandDownregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4The cell surface mucin podocalyxin regulates collective breast tumor budding.Unraveling the microenvironmental influences on the normal mammary gland and breast cancerThe difficulty of targeting cancer stem cell nichesWhy don't we get more cancer? A proposed role of the microenvironment in restraining cancer progressionOf extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroidsRestoration of E-cadherin cell-cell junctions requires both expression of E-cadherin and suppression of ERK MAP kinase activation in Ras-transformed breast epithelial cells.Functional live-cell imaging demonstrates that beta1-integrin promotes type IV collagen degradation by breast and prostate cancer cellsThree-dimensional culture models of normal and malignant breast epithelial cells.Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging.Physical mechanisms redirecting cell polarity and cell shape in fission yeast.Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer.CXCR4 drives the metastatic phenotype in breast cancer through induction of CXCR2 and activation of MEK and PI3K pathwaysFunctional characterization of E- and P-cadherin in invasive breast cancer cells.The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D culturesBMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cellsTargeting of integrin beta1 and kinesin 2alpha by microRNA 183Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogen-activated protein kinase kinase inhibitors.Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells.3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen.HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes.Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoliAlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer.Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109Three dimensional cultures: a tool to study normal acinar architecture vs. malignant transformation of breast cells.
P2860
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P2860
Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Phenotypic reversion or death ...... in three-dimensional contexts
@ast
Phenotypic reversion or death ...... in three-dimensional contexts
@en
Phenotypic reversion or death ...... in three-dimensional contexts
@nl
type
label
Phenotypic reversion or death ...... in three-dimensional contexts
@ast
Phenotypic reversion or death ...... in three-dimensional contexts
@en
Phenotypic reversion or death ...... in three-dimensional contexts
@nl
prefLabel
Phenotypic reversion or death ...... in three-dimensional contexts
@ast
Phenotypic reversion or death ...... in three-dimensional contexts
@en
Phenotypic reversion or death ...... in three-dimensional contexts
@nl
P2093
P2860
P356
P1476
Phenotypic reversion or death ...... in three-dimensional contexts
@en
P2093
Derek Radisky
Eva A Turley
Mary Helen Barcellos-Hoff
Mina J Bissell
Rhonda K Hansen
Toshiyuki Yoneda
P2860
P304
P356
10.1093/JNCI/94.19.1494
P407
P577
2002-10-01T00:00:00Z