Osteopontin induces AP-1-mediated secretion of urokinase-type plasminogen activator through c-Src-dependent epidermal growth factor receptor transactivation in breast cancer cells.
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Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cellsInterleukin enhancer-binding factor 3 promotes breast tumor progression by regulating sustained urokinase-type plasminogen activator expressionRab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.Inhibition of breast cancer cell adhesion and bone metastasis by the extracellular adherence protein of Staphylococcus aureusAptamer-mediated impairment of EGFR-integrin αvβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers.RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells.Deletion of the thrombin cleavage domain of osteopontin mediates breast cancer cell adhesion, proteolytic activity, tumorgenicity, and metastasisElevation of osteopontin levels in brain tumor cells reduces burden and promotes survival through the inhibition of cell dispersalOsteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation.Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancerRegulation of Erk1/2 activation by osteopontin in PC3 human prostate cancer cellsLessons in signaling and tumorigenesis from polyomavirus middle T antigen.Elevated plasma osteopontin associated with gastric cancer development, invasion and survival.Integrin signaling is critical for pathological angiogenesisOsteopontin: an emerging therapeutic target for anticancer therapy.uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo.Inhibition of angiogenesis and invasion in malignant gliomas.Low amount of salinomycin greatly increases Akt activation, but reduces activated p70S6K levelsExtracellular and intracellular mechanisms that mediate the metastatic activity of exogenous osteopontin.Bone sialoprotein and osteopontin in bone metastasis of osteotropic cancersCharacteristics of the level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1.Osteopontin: a potentially important therapeutic target in cancer.Role of osteopontin in the pathophysiology of cancer.Osteopontin as a therapeutic target for cancer.Cytotoxicity of the Urokinase-Plasminogen Activator Inhibitor Carbamimidothioic Acid (4-Boronophenyl) Methyl Ester Hydrobromide (BC-11) on Triple-Negative MDA-MB231 Breast Cancer Cells.Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation.Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.RETRACTED: JNK1 differentially regulates osteopontin-induced nuclear factor-inducing kinase/MEKK1-dependent activating protein-1-mediated promatrix metalloproteinase-9 activation.Nuclear factor-inducing kinase plays a crucial role in osteopontin-induced MAPK/IkappaBalpha kinase-dependent nuclear factor kappaB-mediated promatrix metalloproteinase-9 activation.Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway.Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis.Src kinase activity is required for integrin alphaVbeta3-mediated activation of nuclear factor-kappaB.Osteopontin is a useful predictor of bone metastasis and survival in patients with locally advanced nasopharyngeal carcinoma.Prognostic implications of the co-detection of the urokinase plasminogen activator system and osteopontin in patients with non-small-cell lung cancer undergoing radiotherapy and correlation with gross tumor volume.
P2860
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P2860
Osteopontin induces AP-1-mediated secretion of urokinase-type plasminogen activator through c-Src-dependent epidermal growth factor receptor transactivation in breast cancer cells.
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2004 nî lūn-bûn
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2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2004 թվականի հունվարին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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name
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@ast
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@en
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@nl
type
label
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@ast
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@en
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@nl
prefLabel
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@ast
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@en
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@nl
P2860
P356
P1476
Osteopontin induces AP-1-media ...... vation in breast cancer cells.
@en
P2093
Ganapati H Mahabeleshwar
P2860
P304
11051-11064
P356
10.1074/JBC.M310256200
P407
P50
P577
2004-01-02T00:00:00Z