Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
about
TRIM5α and Species Tropism of HIV/SIVImpact of TRIM5α in vivoNovel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid ProteinStructural insight into HIV-1 capsid recognition by rhesus TRIM5Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α SpecificityThe antiviral spectra of TRIM5α orthologues and human TRIM family proteins against lentiviral production.Recognition of the HIV capsid by the TRIM5α restriction factor is mediated by a subset of pre-existing conformations of the TRIM5α SPRY domain.Ex vivo gene therapy for HIV-1 treatment.Assisted evolution enables HIV-1 to overcome a high TRIM5α-imposed genetic barrier to rhesus macaque tropism.Role of Human TRIM5α in Intrinsic Immunity.Novel mutant human immunodeficiency virus type 1 strains with high degree of resistance to cynomolgus macaque TRIMCyp generated by random mutagenesisPreclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 TransgeneHIV-1 Adapts To Replicate in Cells Expressing Common Marmoset APOBEC3G and BST2A comparison of murine leukemia viruses that escape from human and rhesus macaque TRIM5αs.Characterization of two distinct early post-entry blocks to HIV-1 in common marmoset lymphocytes.Using TRIM5α as an HIV therapeutic: the alpha gene?The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import.
P2860
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P2860
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
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2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@ast
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@en
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@nl
type
label
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@ast
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@en
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@nl
prefLabel
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@ast
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@en
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@nl
P2860
P50
P1433
P1476
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
@en
P2093
Matthew Stremlau
P2860
P304
P356
10.1016/J.VIROL.2010.09.019
P407
P577
2010-10-16T00:00:00Z