CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint. - Wikidata - wikimedia - TriplyDB

CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint.

CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint.

http://www.wikidata.org/entity/Q34288537

about

Mutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfism A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting The spindle checkpoint and chromosome segregation in meiosis The MRN-CtIP pathway is required for metaphase chromosome alignment.Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.Cenp-meta is required for sustained spindle checkpoint Construction of protein phosphorylation networks by data mining, text mining and ontology integration: analysis of the spindle checkpoint.Zwint-1 is required for spindle assembly checkpoint function and kinetochore-microtubule attachment during oocyte meiosis.Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E.Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling Predictive and prognostic values of BubR1 and synuclein-gamma expression in breast cancer Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.A dynein independent role of Tctex-1 at the kinetochore.New insights into the mechanism for chromosome alignment in metaphase Use of the protein ontology for multi-faceted analysis of biological processes: a case study of the spindle checkpoint Making an effective switch at the kinetochore by phosphorylation and dephosphorylation.Mitosis as an anti-cancer drug target.Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.BubR1 shows self-control.Simultaneous reduction of MAD2 and BUBR1 expression induces mitotic spindle alterations associated with p53 dependent cell cycle arrest and death.Epigenetics in Turner syndrome.

P2860

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P2860

CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint.

http://www.wikidata.org/entity/Q34288537

description

2012 nî lūn-bûn

@nan

2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

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2012年論文

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2012年論文

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2012年论文

@wuu

name

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@ast

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@en

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@nl

type

label

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@ast

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@en

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@nl

prefLabel

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@ast

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@en

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@nl

P1433

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P1433

Journal of Cell Biology

P1476

CENP-E--dependent BubR1 autoph ...... nt and the mitotic checkpoint.

@en

P2093

Christine Kim

http://www.w3.org/2001/XMLSchema#string

Jiayin Zhang

http://www.w3.org/2001/XMLSchema#string

Sana Ahmad

http://www.w3.org/2001/XMLSchema#string

Yige Guo

http://www.w3.org/2001/XMLSchema#string

Yinghui Mao

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC

CENP-E is a putative kinetochore motor that accumulates just before mitosis

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility

Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex

Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling

P304

205-217

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scholarly article

P356

10.1083/JCB.201202152

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P433

2

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198

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2012-07-16T00:00:00Z

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229155928

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22801780

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P932

3410423

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