Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function. - Wikidata - wikimedia - TriplyDB

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.

http://www.wikidata.org/entity/Q34295969

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Mechanisms of interstrand DNA crosslink repair and human disorders Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work Modeling the study of DNA damage responses in mice Fanconi anemia and the cell cycle: new perspectives on aneuploidy Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination Fanconi anaemia and the repair of Watson and Crick DNA crosslinks Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia Advances in understanding the complex mechanisms of DNA interstrand cross-link repair Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors Defective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice.DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA.Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia Reduced Competitive Repopulation Capacity of Multipotential Hematopoietic Stem Cells in the Bone Marrow of Friend Virus-infected Fv2-resistant Mice.All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Dark Hydrazone Fluorescence Labeling Agents Enable Imaging of Cellular Aldehydic Load.The endogenous exposome.Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents Metabolic regulation of stem cell function.Maternal aldehyde elimination during pregnancy preserves the fetal genome Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice.Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA via C5 of thymidine Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling.A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.Formation, Accumulation, and Hydrolysis of Endogenous and Exogenous Formaldehyde-Induced DNA Damage.Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia.Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks.ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis.DNA helicases involved in DNA repair and their roles in cancer Chronic alcohol consumption inhibits melanoma growth but decreases the survival of mice immunized with tumor cell lysate and boosted with α-galactosylceramide.The Salivary Microbiome and Oral Cancer Risk: a Pilot Study in Fanconi Anemia.FANCA safeguards interphase and mitosis during hematopoiesis in vivo.ATM and KAT5 safeguard replicating chromatin against formaldehyde damage.Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.

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P2860

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.

http://www.wikidata.org/entity/Q34295969

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2012 nî lūn-bûn

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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2012 թվականի օգոստոսին հրատարակված գիտական հոդված

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2012年の論文

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Genotoxic consequences of endo ...... atopoietic stem cell function.

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Frederic Langevin

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Gerry P Crossan

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Juan I Garaycoechea

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Ketan J Patel

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Maria Daly

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P2860

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

DNA repair is limiting for haematopoietic stem cells during ageing

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

Cell intrinsic alterations underlie hematopoietic stem cell aging.

Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

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10.1038/NATURE11368

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