A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor.
about
Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain sheddingPolymerase chain reaction selects a novel disintegrin proteinase from CD40-activated germinal center dendritic cellsHorror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during InflammationInflammation and Alzheimer's diseaseShedding of membrane type 1 matrix metalloproteinase in a human breast carcinoma cell line.Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion.Differential effects of total and partial neutralization of tumor necrosis factor on cell-mediated immunity to Mycobacterium bovis BCG infection.Pharmacological profile of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-alpha converting enzyme and matrix metalloproteinases, in models of airway inflammationNeuroinflammation in the aging down syndrome brain; lessons from Alzheimer's disease.Sympathetic neurons can produce and respond to interleukin 6Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: a mechanism for generation of soluble cytokine receptors.Soluble interleukin-6 receptor is elevated during influenza A virus infection and mediates the IL-6 and IL-32 inflammatory cytokine burst.Regulation of monocyte MMP-9 production by TNF-alpha and a tumour-derived soluble factor (MMPSF).The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.Interleukin-6 in aging and chronic disease: a magnificent pathwayCleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases.Cytokines as cellular communicatorsCutting edge: soluble IL-6R is produced by IL-6R ectodomain shedding in activated CD4 T cells.Soluble interleukin-6 receptor-mediated innate immune response to DNA and RNA viruses.Role of ADAM17 in invasion and migration of CD133-expressing liver cancer stem cells after irradiation.Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha.ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation.Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.Interleukin-6: a new therapeutic target in systemic sclerosis?Sustained Immune Complex-Mediated Reduction in CD16 Expression after Vaccination Regulates NK Cell Function.ADAM17 promotes glioma cell malignant phenotypeRNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding.Selective killing of human monocytes and cytokine release provoked by sphingomyelinase (beta-toxin) of Staphylococcus aureus.Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptorIL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells.Suppression of LPS-induced inflammatory responses by the hydroxyl groups of dexamethasone.Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseasesMembrane protein secretasesRole of tumour necrosis factor-alpha and other cytokines in ischemia-reperfusion-induced injury in the heart.Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice.Chloroquine decreases cell-surface expression of tumour necrosis factor receptors in human histiocytic U-937 cells.Transmembrane TNF-dependent uptake of anti-TNF antibodies.Mononuclear phagocyte hydrolytic enzyme activity associated with cerebral HIV-1 infection.The effects of interleukin-1beta in tumor necrosis factor-alpha-induced acute pulmonary inflammation in mice
P2860
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P2860
A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor.
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@ast
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@en
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@nl
type
label
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@ast
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@en
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@nl
prefLabel
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@ast
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@en
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@nl
P2093
P1476
A metalloprotease inhibitor bl ...... ptor and the p60 TNF receptor.
@en
P2093
Alderson MR
Müllberg J
Otten-Evans C
Rose-John S
P304
P407
P577
1995-12-01T00:00:00Z