Multiparameter in vitro assessment of compound effects on cardiomyocyte physiology using iPSC cells. - Wikidata - wikimedia - TriplyDB

Multiparameter in vitro assessment of compound effects on cardiomyocyte physiology using iPSC cells.

Multiparameter in vitro assessment of compound effects on cardiomyocyte physiology using iPSC cells.

http://www.wikidata.org/entity/Q34299468

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Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening Generation of highly purified human cardiomyocytes from peripheral blood mononuclear cell-derived induced pluripotent stem cells A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) to Monitor Compound Effects on Cardiac Myocyte Signaling Pathways.Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model.iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types.Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity Small molecule screening in human induced pluripotent stem cell-derived terminal cell types.High throughput physiological screening of iPSC-derived cardiomyocytes for drug development.Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.Pluripotent stem cells as a platform for cardiac arrhythmia drug screening Human stem cell-derived cardiomyocytes in cellular impedance assays: bringing cardiotoxicity screening to the front line.High-throughput drug profiling with voltage- and calcium-sensitive fluorescent probes in human iPSC-derived cardiomyocytes.Induced pluripotent stem cells: at the heart of cardiovascular precision medicine.Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.Convergence of Highly Resolved and Rapid Screening Platforms with Dynamically Engineered, Cell Phenotype-Prescriptive Biomaterials.Can Human Pluripotent Stem Cell-Derived Cardiomyocytes Advance Understanding of Muscular Dystrophies?Evaluation of Batch Variations in Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes from 2 Major Suppliers.High-Content Assessment of Cardiac Function Using Heart-on-a-Chip Devices as Drug Screening Model.Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain.A non-invasive platform for functional characterization of stem-cell-derived cardiomyocytes with applications in cardiotoxicity testing.Bridging Functional and Structural Cardiotoxicity Assays Using Human Embryonic Stem Cell-Derived Cardiomyocytes for a More Comprehensive Risk Assessment.Stem cell derived in vivo-like human cardiac bodies in a microfluidic device for toxicity testing by beating frequency imaging.Enhanced characterization of contractility in cardiomyocytes during early drug safety assessment.High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes A Pipeline for High-Throughput Concentration Response Modeling of Gene Expression for Toxicogenomics.Machine Learning of Human Pluripotent Stem Cell-Derived Engineered Cardiac Tissue Contractility for Automated Drug Classification.Evaluation of drug-mediated arrhythmic changes in spontaneous beating cardiomyocytes by AFM.The Need for, and the Role of the Toxicological Chemist in the Design of Safer Chemicals.Human pluripotent stem cell-derived cardiomyocyte based models for cardiotoxicity and drug discovery.Multielectrode Array (MEA) Assay for Profiling Electrophysiological Drug Effects in Human Stem Cell-Derived Cardiomyocytes.On-chip spatiotemporal electrophysiological analysis of human stem cell derived cardiomyocytes enables quantitative assessment of proarrhythmia in drug development

P2860

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P2860

Multiparameter in vitro assessment of compound effects on cardiomyocyte physiology using iPSC cells.

http://www.wikidata.org/entity/Q34299468

description

2012 nî lūn-bûn

@nan

2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Multiparameter in vitro assess ...... e physiology using iPSC cells.

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Multiparameter in vitro assess ...... e physiology using iPSC cells.

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Multiparameter in vitro assess ...... e physiology using iPSC cells.

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Multiparameter in vitro assess ...... e physiology using iPSC cells.

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Multiparameter in vitro assess ...... e physiology using iPSC cells.

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Multiparameter in vitro assess ...... e physiology using iPSC cells.

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Multiparameter in vitro assess ...... e physiology using iPSC cells.

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Multiparameter in vitro assess ...... e physiology using iPSC cells.

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P2093

Blake Anson

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Carlos Funes

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Carole Crittenden

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Evan F Cromwell

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Ivan Rusyn

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Jayne Hesley

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Nick Callamaras

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Oksana Sirenko

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Yen-Wen Chen

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P2860

Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle

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Can the pharmaceutical industry reduce attrition rates?

The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel.

The impact of drug-induced QT interval prolongation on drug discovery and development.

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.

The effect of verapamil and other calcium antagonists on chemotaxis of polymorphonuclear leukocytes.

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Local Ca(2+) signaling and EC coupling in heart: Ca(2+) sparks and the regulation of the [Ca(2+)](i) transient.

How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

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39-53

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230843440

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22972846

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