Identification of the A2 adenosine receptor binding subunit by photoaffinity crosslinking.
about
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor125I-4-(2-[7-amino-2-[2-furyl][1,2,4]triazolo[2,3-a][1,3,5] triazin-5-yl-amino]ethyl)phenol, a high affinity antagonist radioligand selective for the A2a adenosine receptorHydrophilic side chains in the third and seventh transmembrane helical domains of human A2A adenosine receptors are required for ligand recognitionEvaluation of homology modeling of G-protein-coupled receptors in light of the A(2A) adenosine receptor crystallographic structure.Molecular probes for muscarinic receptors: functionalized congeners of selective muscarinic antagonistsAdenosine and ischemic preconditioning.Functionalized congener approach to the design of ligands for G protein-coupled receptors (GPCRs).Adenosine modulation of neurotransmission in penile erection.Agonist derived molecular probes for A2 adenosine receptorsAdenosine A1 and A2 receptors: structure--function relationshipsA2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase.8-(3-Isothiocyanatostyryl)caffeine Is a Selective, Irreversible Inhibitor of Striatal A(2)-Adenosine ReceptorsCharacterization of human striatal A2-adenosine receptors using radioligand binding and photoaffinity labelingChemical modification and irreversible inhibition of striatal A2a adenosine receptors.Mutagenesis reveals structure-activity parallels between human A2A adenosine receptors and biogenic amine G protein-coupled receptors.Glycoprotein nature of the A2-adenosine receptor binding subunitThe A2 adenosine receptor: guanine nucleotide modulation of agonist binding is enhanced by proteolysis.Characterization of the locomotor depression produced by an A2-selective adenosine agonist.Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.[(3)H]XAC (xanthine amine congener) is a radioligand for A(2)-adenosine receptors in rabbit striatum.Solubilized rabbit striatal A2a-adenosine receptors: stability and antagonist bindingNeurobiological applications of small molecule screening.Purine nucleosides and nucleotides as central nervous system modulators. Adenosine as the prototypic paracrine neuroactive substance.Biochemical properties of a P2Y-purinergic receptor.Affinity purification in target identification: the specificity challenge.Elucidating the role of the A2A adenosine receptor in neurodegeneration using neurons derived from Huntington's disease iPSCs.Functionalized congeners of tyrosine-based P2X(7) receptor antagonists: probing multiple sites for linking and dimerization.The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.Immunological identification of A2 adenosine receptors by two antipeptide antibody preparations.Distinct pathways of desensitization of A1- and A2-adenosine receptors in DDT1 MF-2 cells.Demonstration of both A1 and A2 adenosine receptors in DDT1 MF-2 smooth muscle cellsA covalent antagonist for the human adenosine A2A receptor.Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists.Solubilization and characterization of the A2-adenosine receptor.
P2860
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P2860
Identification of the A2 adenosine receptor binding subunit by photoaffinity crosslinking.
description
1989 nî lūn-bûn
@nan
1989 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@ast
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@en
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@nl
type
label
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@ast
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@en
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@nl
prefLabel
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@ast
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@en
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@nl
P2093
P2860
P356
P1476
Identification of the A2 adeno ...... by photoaffinity crosslinking.
@en
P2093
A J Hutchison
G L Stiles
K A Jacobson
M Williams
W W Barrington
P2860
P304
P356
10.1073/PNAS.86.17.6572
P407
P577
1989-09-01T00:00:00Z