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Adenosine A1 and A2 receptors: structure--function relationships

Adenosine A1 and A2 receptors: structure--function relationships

http://www.wikidata.org/entity/Q35766866

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Adenosine receptors and asthma in humans Hydrophilic side chains in the third and seventh transmembrane helical domains of human A2A adenosine receptors are required for ligand recognition Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats "Cleavable trifunctional" approach to receptor affinity labeling: chemical regeneration of binding to A1-adenosine receptors Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors A binding site model and structure-activity relationships for the rat A3 adenosine receptor Coupling of a transfected human brain A1 adenosine receptor in CHO-K1 cells to calcium mobilisation via a pertussis toxin-sensitive mechanism Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists Mechanism of adenosine-induced vasodilation in rat diaphragm microcirculation.Adenosine and hemodialysis in humans.Persistent activation by and receptor reserve for an irreversible A1-adenosine receptor agonist in DDT1 MF-2 cells and in guinea pig heart.Nomenclature and classification of purinoceptors.Functional characterization of the adenosine receptor mediating inhibition of intestinal secretion.Stimulation of human umbilical vein endothelial cell proliferation by A2-adenosine and beta 2-adrenoceptors.A role for central A3-adenosine receptors. Mediation of behavioral depressant effects Molecular Architecture of G Protein-Coupled Receptors.A comparison of A2 adenosine receptor-induced cyclic AMP generation in cerebral cortex and relaxation of pre-contracted aorta 8-(3-Isothiocyanatostyryl)caffeine Is a Selective, Irreversible Inhibitor of Striatal A(2)-Adenosine Receptors Glutamate residues in the second extracellular loop of the human A2a adenosine receptor are required for ligand recognition.Chemical modification and irreversible inhibition of striatal A2a adenosine receptors.Molecular Characterization of A(1) and A(2a) Adenosine Receptors.Adenosine receptor-induced second messenger production in adult guinea-pig cerebellum Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo A SURVEY OF NONXANTHINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS.Solubilized rabbit striatal A2a-adenosine receptors: stability and antagonist binding Adenosine and blood platelets.A2 adenosine receptors and vascular pathologies.Comparative molecular field analysis of selective A3 adenosine receptor agonists.Desensitization of the canine A2a adenosine receptor: delineation of multiple processes.Adenosine A1 receptor agonists as clinically viable agents for treatment of ischemic brain disorders.Immunological identification of A2 adenosine receptors by two antipeptide antibody preparations.Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds.Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor.Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists.Effects of the new A2 adenosine receptor antagonist 8FB-PTP, an 8 substituted pyrazolo-triazolo-pyrimidine, on in vitro functional models Xanthine scaffold: scope and potential in drug development

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P2860

Adenosine A1 and A2 receptors: structure--function relationships

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1992 nî lūn-bûn

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Adenosine A1 and A2 receptors: structure--function relationships

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Adenosine A1 and A2 receptors: structure--function relationships

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Medicinal Research Reviews

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Adenosine A1 and A2 receptors: structure--function relationships

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G L Stiles

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G Michaels

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K A Jacobson

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P J van Galen

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P2860

Non-xanthine heterocycles: activity as antagonists of A1- and A2-adenosine receptors

A comprehensive set of sequence analysis programs for the VAX

A simple method for displaying the hydropathic character of a protein

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

Prediction of protein conformation

Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor

Selective amplification and cloning of four new members of the G protein-coupled receptor family

A novel multigene family may encode odorant receptors: a molecular basis for odor recognition

Caffeine analogs: structure-activity relationships at adenosine receptors

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10.1002/MED.2610120502

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