On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
about
Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid bindingIMP dehydrogenase: structure, mechanism, and inhibition.Why do mutations in the ubiquitously expressed housekeeping gene IMPDH1 cause retina-specific photoreceptor degeneration?Spectrum and frequency of mutations in IMPDH1 associated with autosomal dominant retinitis pigmentosa and leber congenital amaurosisIMP dehydrogenase type 1 associates with polyribosomes translating rhodopsin mRNAPhenotypic characterization of a large family with RP10 autosomal-dominant retinitis pigmentosa: an Asp226Asn mutation in the IMPDH1 geneRetinal isoforms of inosine 5'-monophosphate dehydrogenase type 1 are poor nucleic acid binding proteinsA regulatory role of the Bateman domain of IMP dehydrogenase in adenylate nucleotide biosynthesisDifferent characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoformsCrystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulationNeural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeletonConstituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degenerationInvestigating the mechanism of disease in the RP10 form of retinitis pigmentosa.Novel direct targets of miR-19a identified in breast cancer cells by a quantitative proteomic approach.Clinical phenotype in a Swedish family with a mutation in the IMPDH1 gene.Let-7, mir-98 and mir-183 as biomarkers for cancer and schizophrenia [corrected]Effect of rapamycin on the fate of P23H opsin associated with retinitis pigmentosa (an American Ophthalmological Society thesis).Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases.High-resolution analysis of the human retina miRNome reveals isomiR variations and novel microRNAs.Molecular chaperones and photoreceptor function.IMP dehydrogenase-linked retinitis pigmentosa.An experimental platform for systemic drug delivery to the retina.Detecting genetic variations in hereditary retinal dystrophies with next-generation sequencing technology.Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP.Inhibitor mediated protein degradation.Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90).Reprogramming the metabolome rescues retinal degeneration.
P2860
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P2860
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
description
2004 nî lūn-bûn
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2004 թուականի Մարտին հրատարակուած գիտական յօդուած
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2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
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name
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@ast
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@en
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@nl
type
label
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@ast
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@en
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@nl
prefLabel
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@ast
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@en
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
@nl
P2093
P356
P1476
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa
@en
P2093
Aileen Aherne
Anna-Sophia Kiang
Avril Kennan
Beverly S Mitchell
G Jane Farrar
Ian L Alberts
Jing Jin Gu
Marian M Humphries
Niamh McNally
Paul C Engel
P304
P356
10.1093/HMG/DDH061
P577
2004-03-01T00:00:00Z