Clustered basic residues within segment 484-510 of the factor VIIIa A2 subunit contribute to the catalytic efficiency for factor Xa generation.

Clustered basic residues within segment 484-510 of the factor VIIIa A2 subunit contribute to the catalytic efficiency for factor Xa generation.

Item
http://www.wikidata.org/entity/Q34304145
Epitope mapping factor VIII A2 domain by affinity-directed mass spectrometry: residues 497-510 and 584-593 comprise a discontinuous epitope for the monoclonal antibody R8B12.Structural investigation of zymogenic and activated forms of human blood coagulation factor VIII: a computational molecular dynamics studyEffects of replacement of factor VIII amino acids Asp519 and Glu665 with Val on plasma survival and efficacy in vivo.Role of the residues of the 39-loop in determining the substrate and inhibitor specificity of factor IXa.Soy phosphatidylinositol containing nanoparticle prolongs hemostatic activity of B-domain deleted factor VIII in hemophilia A mice.Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites.Factor VIII associated with lipidic nanoparticles retains efficacy in the presence of anti-factor VIII antibodies in hemophilia A mice.Depolymerized holothurian glycosaminoglycan and heparin inhibit the intrinsic tenase complex by a common antithrombin-independent mechanism.Mapping of the factor Xa binding site on factor Va by site-directed mutagenesis
P2860

Clustered basic residues within segment 484-510 of the factor VIIIa A2 subunit contribute to the catalytic efficiency for factor Xa generation.

Item
http://www.wikidata.org/entity/Q34304145
description
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2004年論文
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name
Clustered basic residues withi ...... ency for factor Xa generation.
@ast
Clustered basic residues withi ...... ency for factor Xa generation.
@en
Clustered basic residues withi ...... ency for factor Xa generation.
@nl
type
label
Clustered basic residues withi ...... ency for factor Xa generation.
@ast
Clustered basic residues withi ...... ency for factor Xa generation.
@en
Clustered basic residues withi ...... ency for factor Xa generation.
@nl
prefLabel
Clustered basic residues withi ...... ency for factor Xa generation.
@ast
Clustered basic residues withi ...... ency for factor Xa generation.
@en
Clustered basic residues withi ...... ency for factor Xa generation.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Clustered basic residues withi ...... iency for factor Xa generation
@en
P2093
P2860
P304
P31
P356
10.1111/J.1538-7933.2004.00625.X
P433
P478
P50
P577
P5875
P698