Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies
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G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human plateletsAnalysis of the relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these polypeptides in rat 1 fibroblastsThrombin inhibits the pertussis-toxin-dependent ADP-ribosylation of a novel soluble Gi-protein in human plateletsMembrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 cellsCharacterization and distribution of alpha 2-adrenergic receptors in the human intestinal mucosaPlatelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responsesCoupling of the alpha 2-adrenergic receptor to the inhibitory G-protein Gi and adenylate cyclase in HT29 cellsBinding of G alpha(o) N terminus is responsible for the voltage-resistant inhibition of alpha(1A) (P/Q-type, Ca(v)2.1) Ca(2+) channelsThe alpha 2B adrenergic receptor of undifferentiated neuroblastoma x glioma hybrid NG108-15 cells, interacts directly with the guanine nucleotide binding protein, Gi2Control of the expression and activity of the Galpha-interacting protein (GAIP) in human intestinal cellsAgonist trafficking of G(i/o)-mediated alpha(2A)-adrenoceptor responses in HEL 92.1.7 cellsAdenylyl cyclase inhibition and altered G protein subunit expression and ADP-ribosylation patterns in tissues and cells from Gi2 alpha-/-miceThe human platelet ADP receptor activates Gi2 proteinsIdentification of the in vitro phosphorylation sites on Gs alpha mediated by pp60c-src.Inhibition of human platelet adenylate cyclase activity by adrenaline, thrombin and collagen: analysis and reinterpretation of experimental data.Levels of G-proteins in liver and brain of lean and obese (ob/ob) miceMicrosomal and cytosolic fractions of guinea pig hepatocytes contain 100-kilodalton GTP-binding proteins reactive with antisera against alpha subunits of stimulatory and inhibitory heterotrimeric GTP-binding proteins.Octyl glucoside extracts GTP-binding regulatory proteins from rat brain "synaptoneurosomes" as large, polydisperse structures devoid of beta gamma complexes and sensitive to disaggregation by guanine nucleotides.The G proteins of the G alpha i and G alpha q family couple the bradykinin receptor to the release of endothelium-derived relaxing factor.An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex functionCholera toxin inhibits signal transduction by several mitogens and the in vitro growth of human small-cell lung cancerThrombin regulates intracellular cyclic AMP concentration in human platelets through phosphorylation/activation of phosphodiesterase 3A.Endoplasmic reticulum-through-Golgi transport assay based on O-glycosylation of native glycophorin in permeabilized erythroleukemia cells: role for Gi3.Mediation of growth factor induced DNA synthesis and calcium mobilization by Gq and Gi2Oocyte maturation in starfish is mediated by the beta gamma-subunit complex of a G-proteinGo mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain.Stimulation of Xenopus oocyte maturation by inhibition of the G-protein alpha S subunit, a component of the plasma membrane and yolk platelet membranes.Gi2 and protein kinase C are required for thyrotropin-releasing hormone-induced stimulation of voltage-dependent Ca2+ channels in rat pituitary GH3 cells.The nature and origin of spontaneous noise in G protein-gated ion channels.Stimulus-induced dissociation of alpha subunits of heterotrimeric GTP-binding proteins from the cytoskeleton of human neutrophils.A heterotrimeric G protein, G alpha i-3, on Golgi membranes regulates the secretion of a heparan sulfate proteoglycan in LLC-PK1 epithelial cells.Analysis of the receptor binding domain of Gpa1p, the G(alpha) subunit involved in the yeast pheromone response pathwayPheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae.Occurrence of the alpha subunits of G proteins in cerebral cortex synaptic membrane and postsynaptic density fractions: modulation of ADP-ribosylation by Ca2+/calmodulin.Generation of mouse oocytes defective in cAMP synthesis and degradation: endogenous cyclic AMP is essential for meiotic arrest.Drosophila stimulatory G protein alpha subunit activates mammalian adenylyl cyclase but interacts poorly with mammalian receptors: implications for receptor-G protein interaction.Analysis of stimulation-G protein subunit coupling by using active insulin-like growth factor II receptor peptideA blue-light-activated GTP-binding protein in the plasma membranes of etiolated peasActivating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells.The control of blood platelets by cAMP signalling.
P2860
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P2860
Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies
description
1989 nî lūn-bûn
@nan
1989 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@ast
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@en
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@nl
type
label
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@ast
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@en
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@nl
prefLabel
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@ast
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@en
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@nl
P2093
P2860
P356
P1476
Gi2 mediates alpha 2-adrenergi ...... G alpha C-terminal antibodies
@en
P2093
A M Spiegel
P K Goldsmith
W F Simonds
P2860
P304
P356
10.1073/PNAS.86.20.7809
P407
P577
1989-10-01T00:00:00Z