The CD27 and CD70 costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity.
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Role of Tumor Necrosis Factor Superfamily in Neuroinflammation and AutoimmunityNeuroprotection in a novel mouse model of multiple sclerosisTargeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potentialStimulating CD27 to quantitatively and qualitatively shape adaptive immunity to cancer.Dual function of CD70 in viral infection: modulator of early cytokine responses and activator of adaptive responses.Phase I dose-escalation study of SGN-75 in patients with CD70-positive relapsed/refractory non-Hodgkin lymphoma or metastatic renal cell carcinoma.Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+ T Cell Expression of IL-22 and Mucosal Release of CalprotectinAntifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFNγ cellsIn vivo photolabeling of tumor-infiltrating cells reveals highly regulated egress of T-cell subsets from tumors.Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity.Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathwayGenetic background can result in a marked or minimal effect of gene knockout (GPR55 and CB2 receptor) in experimental autoimmune encephalomyelitis models of multiple sclerosis.Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation.C-Myc regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection.Essentials of Th17 cell commitment and plasticityViral Persistence Induces Antibody Inflation without Altering Antibody AvidityCo-stimulatory and Co-inhibitory Pathways in Autoimmunity.Peripheral and thymic foxp3(+) regulatory T cells in search of origin, distinction, and functionMechanisms of Cholera Toxin in the Modulation of TH17 Responses.Analysis of the cross-talk of Epstein-Barr virus-infected B cells with T cells in the marmoset.The nature of activatory and tolerogenic dendritic cell-derived signal II.Epigenetics of multiple sclerosis: an updated review.Th17 cells in autoimmune diseases.The importance of co-stimulation in the orchestration of T helper cell differentiation.Molecular Mechanisms of the Action of Vitamin A in Th17/Treg Axis in Multiple Sclerosis.Therapeutic targeting of CD70 and CD27.Dendritic cells as gatekeepers of tolerance.Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function.The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansion.Tregs strip dendritic cells of CD70 to regulate Th1 differentiation.The CD70-CD27 axis, a new brake in the T helper 17 cell response.CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection.Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications.T Cell-Derived CD70 Delivers an Immune Checkpoint Function in Inflammatory T Cell Responses.The Fos-Related Antigen 1-JUNB/Activator Protein 1 Transcription Complex, a Downstream Target of Signal Transducer and Activator of Transcription 3, Induces T Helper 17 Differentiation and Promotes Experimental Autoimmune Arthritis.The shortening telomere length of T lymphocytes maybe associated with hyper‑function in servere aplastic anemia.CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice.Immune Checkpoint Inhibitors to Treat Malignant Lymphomas.
P2860
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P2860
The CD27 and CD70 costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@ast
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@en
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@nl
type
label
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@ast
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@en
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@nl
prefLabel
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@ast
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@en
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@nl
P2093
P1433
P1476
The CD27 and CD70 costimulator ...... uates associated autoimmunity.
@en
P2093
Elise A M Veraar
Gerda van der Horst
Heinz Jacobs
Jannie Borst
Jonathan M Coquet
Sabine Middendorp
Yanling Xiao
P356
10.1016/J.IMMUNI.2012.09.009
P407
P577
2012-11-15T00:00:00Z