The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
about
Pregnane X receptor and natural products: beyond drug-drug interactionsActivation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Pregnane X receptor is SUMOylated to repress the inflammatory response.Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes.Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes.In vitro cytochrome p450 formation of a mono-hydroxylated metabolite of zearalenone exhibiting estrogenic activities: possible occurrence of this metabolite in vivo.Regulation of PXR and CAR by protein-protein interaction and signaling crosstalk.Zearalenone (ZEN) and Its Influence on Regulation of Gene Expression in Carp (Cyprinus carpio L.) Liver Tissue.Immunomodulation by Zearalenone in Carp (Cyprinus carpio L.).In vivo effects of zearalenone on the expression of proteins involved in the detoxification of rat xenobiotics.Scientific Opinion on the risks for public health related to the presence of zearalenone in foodRisks for animal health related to the presence of zearalenone and its modified forms in feedNatural feed contaminant zearalenone decreases the expressions of important pro- and anti-inflammatory mediators and mitogen-activated protein kinase/NF-κB signalling molecules in pigs.
P2860
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P2860
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@ast
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@en
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@nl
type
label
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@ast
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@en
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@nl
prefLabel
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@ast
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@en
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@nl
P2093
P2860
P356
P1476
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
@en
P2093
Jeff L Staudinger
Kristin Lichti
Xunshan Ding
P2860
P304
P356
10.1093/TOXSCI/KFJ163
P577
2006-03-17T00:00:00Z