A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.
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The role of PfEMP1 adhesion domain classification in Plasmodium falciparum pathogenesis researchThe role of PfEMP1 as targets of naturally acquired immunity to childhood malaria: prospects for a vaccineThe role of EPCR in the pathogenesis of severe malariaSingle molecule and multiple bond characterization of catch bond associated cytoadhesion in malaria.Cytoadherence phenotype of Plasmodium falciparum-infected erythrocytes is associated with specific pfemp-1 expression in parasites from children with cerebral malariaAntibody recognition of Plasmodium falciparum infected red blood cells by symptomatic and asymptomatic individuals in the Brazilian Amazon.Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains.Interaction between Endothelial Protein C Receptor and Intercellular Adhesion Molecule 1 to Mediate Binding of Plasmodium falciparum-Infected Erythrocytes to Endothelial Cells.The structural basis for CD36 binding by the malaria parasite.EPCR and Malaria Severity: The Center of a Perfect Storm.The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.Differential PfEMP1 expression is associated with cerebral malaria pathology.An assessment of the impact of host polymorphisms on Plasmodium falciparum var gene expression patterns among Kenyan childrenStructure-function-immunogenicity studies of PfEMP1 domain DBL2βPF11_0521, a malaria parasite ligand for ICAM-1.Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.Transfected HEK293 cells expressing functional recombinant intercellular adhesion molecule 1 (ICAM-1)--a receptor associated with severe Plasmodium falciparum malaria.CD36 recruits α₅β₁ integrin to promote cytoadherence of P. falciparum-infected erythrocytes.Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria.An analysis of the binding characteristics of a panel of recently selected ICAM-1 binding Plasmodium falciparum patient isolatesNetwork-based gene prediction for Plasmodium falciparum malaria towards genetics-based drug discovery.α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes.IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria.Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malariaMultiple Plasmodium falciparum Erythrocyte Membrane Protein 1 Variants per Genome Can Bind IgM via Its Fc Fragment FcμMapping the Binding Site of a Cross-Reactive Plasmodium falciparum PfEMP1 Monoclonal Antibody Inhibitory of ICAM-1 Binding.Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria.Maintenance of phenotypic diversity within a set of virulence encoding genes of the malaria parasite Plasmodium falciparum.Diversity of the var gene family of Indonesian Plasmodium falciparum isolates.Progress and prospects for blood-stage malaria vaccinesSevere adult malaria is associated with specific PfEMP1 adhesion types and high parasite biomass.Plasmodium falciparum picks (on) EPCR.Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.The immunological balance between host and parasite in malaria.Characterisation of Plasmodium falciparum populations selected on the human endothelial receptors P-selectin, E-selectin, CD9 and CD151.In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36.Variant surface antigens of Plasmodium falciparum and their roles in severe malaria.Investigating the function of Fc-specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting.Patterns of protective associations differ for antibodies to P.falciparum-infected erythrocytes and merozoites in immunity against malaria in children.Population genomics of virulence genes of Plasmodium falciparum in clinical isolates from Uganda.A re-assessment of gene-tag classification approaches for describing var gene expression patterns during human Plasmodium falciparum malaria parasite infections.
P2860
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P2860
A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@ast
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@en
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@nl
type
label
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@ast
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@en
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@nl
prefLabel
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@ast
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@en
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@nl
P2093
P2860
P50
P356
P1476
A novel domain cassette identi ...... dhesion-inhibitory antibodies.
@en
P2093
Anja T R Jensen
Louise Joergensen
Thomas S Rask
P2860
P304
P356
10.4049/JIMMUNOL.1202578
P407
P50
P577
2012-12-03T00:00:00Z