Inappropriate p53 activation during development induces features of CHARGE syndrome. - Wikidata - wikimedia - TriplyDB

Inappropriate p53 activation during development induces features of CHARGE syndrome.

Inappropriate p53 activation during development induces features of CHARGE syndrome.

http://www.wikidata.org/entity/Q34315506

about

Chromodomain-helicase-DNA binding protein 5, 7 and pronecrotic mixed lineage kinase domain-like protein serve as potential prognostic biomarkers in patients with resected pancreatic adenocarcinomas Functional Insights into Chromatin Remodelling from Studies on CHARGE Syndrome Chromodomain helicase DNA-binding proteins in stem cells and human developmental diseases New insights into craniofacial malformations A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms Epigenetic regulation in the inner ear and its potential roles in development, protection, and regeneration.Harnessing molecular motors for nanoscale pulldown in live cells.The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation.Epigenetic Developmental Disorders: CHARGE syndrome, a case study Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous niche TAp73 transcriptionally represses BNIP3 expression.Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells.Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation.Methylated microRNA genes of the developing murine palate β-Catenin C-terminal signals suppress p53 and are essential for artery formation.Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53.CHD7 promotes proliferation of neural stem cells mediated by MIF.The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger.Huntington Disease as a Neurodevelopmental Disorder and Early Signs of the Disease in Stem Cells.The Transactivation Domains of the p53 Protein.Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development.p53: key conductor of all anti-acne therapies.The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain.The Mendelian disorders of the epigenetic machinery.Versatile Roles of the Chromatin Remodeler CHD7 during Brain Development and Disease.Exome Sequencing Identification of EP300 Mutation in a Proband with Coloboma and Imperforate Anus: Possible Expansion of the Phenotypic Spectrum of Rubinstein-Taybi Syndrome.Guilty as CHARGED: p53's expanding role in disease.ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome.Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome.UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome.A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.Functional Analyses of a Novel Splice Variant in the CHD7 Gene, Found by Next Generation Sequencing, Confirm Its Pathogenicity in a Spanish Patient and Diagnose Him with CHARGE Syndrome.Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders.The Guardian of the Genome Revisited: p53 Downregulates Genes Required for Telomere Maintenance, DNA Repair, and Centromere Structure.Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8

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P2860

Inappropriate p53 activation during development induces features of CHARGE syndrome.

http://www.wikidata.org/entity/Q34315506

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Inappropriate p53 activation during development induces features of CHARGE syndrome.

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Inappropriate p53 activation during development induces features of CHARGE syndrome.

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Inappropriate p53 activation during development induces features of CHARGE syndrome.

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type

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Inappropriate p53 activation during development induces features of CHARGE syndrome.

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Inappropriate p53 activation during development induces features of CHARGE syndrome.

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Inappropriate p53 activation during development induces features of CHARGE syndrome.

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prefLabel

Inappropriate p53 activation during development induces features of CHARGE syndrome.

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Inappropriate p53 activation during development induces features of CHARGE syndrome.

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Inappropriate p53 activation during development induces features of CHARGE syndrome.

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Inappropriate p53 activation during development induces features of CHARGE syndrome.

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Chieh-Yu Lin

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Chien-Jung Lin

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Ching-Pin Chang

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Colleen A Brady

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Donald L Swiderski

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Donna M Martin

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Hannes Vogel

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Heiyoun Jung

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Joanna Wysocka

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Jonathan A Bernstein

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P2860

CHARGE syndrome: the phenotypic spectrum of mutations in the CHD7 gene

Spectrum of CHD7 mutations in 110 individuals with CHARGE syndrome and genotype-phenotype correlation.

CHD7 cooperates with PBAF to control multipotent neural crest formation

Molecular and phenotypic aspects of CHD7 mutation in CHARGE syndrome

Multiple mutations in mouse Chd7 provide models for CHARGE syndrome

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

p53 mutant mice that display early ageing-associated phenotypes

The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear.

Phenotypic spectrum of CHARGE syndrome in fetuses with CHD7 truncating mutations correlates with expression during human development.

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10.1038/NATURE13585

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7521

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514

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Tania Attié-Bitach

Daniel R Fuentes

Jeanine L Van Nostrand

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2014-08-03T00:00:00Z

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264796235

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