Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitors

Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitors

Item
http://www.wikidata.org/entity/Q34318436
Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA.Synthesis and discovery of 18α-GAMG as anticancer agent in vitro and in vivo via down expression of protein p65.Phenyl 1,2,3-triazole-thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3'-azido deoxythymidine.Recent advances in targeting the telomeric G-quadruplex DNA sequence with small molecules as a strategy for anticancer therapies.New dimeric carbazole-benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer.Novel Oligopyrrole Carboxamide based Nickel(II) and Palladium(II) Salens, Their Targeting of Human G-Quadruplex DNA, and Selective Cancer Cell Toxicity.Stabilization of human telomeric G-quadruplex and inhibition of telomerase activity by propeller-shaped trinuclear Pt(II) complexes.Solution structures of multiple G-quadruplex complexes induced by a platinum(II)-based tripod reveal dynamic binding
P2860

Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitors

Item
http://www.wikidata.org/entity/Q34318436
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
@zh-mo
2012年論文
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2012年论文
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name
Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
@en
Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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type
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Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
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P1476
Binding of gemini bisbenzimida ...... f potent telomerase inhibitors
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P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0039467
P407
P433
P478
P50
P577
P5875
P698
P932