Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms

Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms

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http://www.wikidata.org/entity/Q28472826
Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancerProteomic and microRNA data clarifying the effects of telomere shortening on cancer cells.Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitorsThe telomere/telomerase binding factor PinX1 is a new target to improve the radiotherapy effect of oesophageal squamous cell carcinomas.A yeast chemical genetic screen identifies inhibitors of human telomerase.XRCC3 is a promising target to improve the radiotherapy effect of esophageal squamous cell carcinoma.Telomerase as a useful target in cancer fighting-the breast cancer case.Telomere shortening and Alzheimer's disease.Differential downregulation of telomerase activity by bortezomib in multiple myeloma cells-multiple regulatory pathways in vitro and ex vivo.Effect of targeted silencing of hTERT mRNA by lentivirus-mediated siRNA on A549 lung cancer cells in vitro.The combined use of known antiviral reverse transcriptase inhibitors AZT and DDI induce anticancer effects at low concentrations.Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation.Keeping those telomeres short! an innovative intratumoral long-term drug delivery system.Oligonucleotides Targeting Telomeres and Telomerase in Cancer
P2860

Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms

Item
http://www.wikidata.org/entity/Q28472826
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2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Telomere shortening sensitizes ...... tudies and putative mechanisms
@ast
Telomere shortening sensitizes ...... tudies and putative mechanisms
@en
Telomere shortening sensitizes ...... tudies and putative mechanisms
@nl
type
label
Telomere shortening sensitizes ...... tudies and putative mechanisms
@ast
Telomere shortening sensitizes ...... tudies and putative mechanisms
@en
Telomere shortening sensitizes ...... tudies and putative mechanisms
@nl
prefLabel
Telomere shortening sensitizes ...... tudies and putative mechanisms
@ast
Telomere shortening sensitizes ...... tudies and putative mechanisms
@en
Telomere shortening sensitizes ...... tudies and putative mechanisms
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Telomere shortening sensitizes ...... tudies and putative mechanisms
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0009132
P407
P433
P478
P577
P5875
P698
P921
P932