Requirement of multiple cis-acting elements in the human cytomegalovirus major immediate-early distal enhancer for viral gene expression and replication.
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The human cytomegalovirus UL76 gene regulates the level of expression of the UL77 gene.Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication.Phorbol ester-induced human cytomegalovirus major immediate-early (MIE) enhancer activation through PKC-delta, CREB, and NF-kappaB desilences MIE gene expression in quiescently infected human pluripotent NTera2 cells.Inhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication.The human cytomegalovirus major immediate-early enhancer determines the efficiency of immediate-early gene transcription and viral replication in permissive cells at low multiplicity of infection.An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis.Role of the human cytomegalovirus major immediate-early promoter's 19-base-pair-repeat cyclic AMP-response element in acutely infected cells.The human cytomegalovirus gene products essential for late viral gene expression assemble into prereplication complexes before viral DNA replication.The human cytomegalovirus UL133-138 gene locus attenuates the lytic viral cycle in fibroblasts.The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesisReversal of human cytomegalovirus major immediate-early enhancer/promoter silencing in quiescently infected cells via the cyclic AMP signaling pathway.The autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding.Differentiation-Coupled Induction of Human Cytomegalovirus Replication by Union of the Major Enhancer Retinoic Acid, Cyclic AMP, and NF-κB Response Elements.A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication.Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts.In vivo competence of murine cytomegalovirus under the control of the human cytomegalovirus major immediate-early enhancer in the establishment of latency and reactivation.Neutrality of the canonical NF-kappaB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro.Multiple Transcripts Encode Full-Length Human Cytomegalovirus IE1 and IE2 Proteins during Lytic Infection.Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression.Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication.Coordination of late gene transcription of human cytomegalovirus with viral DNA synthesis: recombinant viruses as potential therapeutic vaccine candidates.High-throughput screening of a GlaxoSmithKline protein kinase inhibitor set identifies an inhibitor of human cytomegalovirus replication that prevents CREB and histone H3 post-translational modification.The human cytomegalovirus gene UL79 is required for the accumulation of late viral transcripts.The activator protein 1 binding motifs within the human cytomegalovirus major immediate-early enhancer are functionally redundant and act in a cooperative manner with the NF-{kappa}B sites during acute infectionKaposi sarcoma-associated herpes virus (KSHV) G protein-coupled receptor (vGPCR) activates the ORF50 lytic switch promoter: a potential positive feedback loop for sustained ORF50 gene expressionBreaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells.Amino acid 1-209 is essential for PDX-1-mediated repression of human CMV IE promoter activity.Human cytomegalovirus tegument protein ppUL35 is important for viral replication and particle formationPDX1, a cellular homeoprotein, binds to and regulates the activity of human cytomegalovirus immediate early promoter.Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection.Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction.Murine cytomegalovirus major immediate-early enhancer region operating as a genetic switch in bidirectional gene pair transcription.The 5' Untranslated Region of the Major Immediate Early mRNA is Necessary for Efficient Human Cytomegalovirus Replication.Renal Ischemia/Reperfusion Injury Activates the Enhancer Domain of the Human Cytomegalovirus Major Immediate Early Promoter
P2860
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P2860
Requirement of multiple cis-acting elements in the human cytomegalovirus major immediate-early distal enhancer for viral gene expression and replication.
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Requirement of multiple cis-ac ...... ne expression and replication.
@ast
Requirement of multiple cis-ac ...... ne expression and replication.
@en
Requirement of multiple cis-ac ...... ne expression and replication.
@nl
type
label
Requirement of multiple cis-ac ...... ne expression and replication.
@ast
Requirement of multiple cis-ac ...... ne expression and replication.
@en
Requirement of multiple cis-ac ...... ne expression and replication.
@nl
prefLabel
Requirement of multiple cis-ac ...... ne expression and replication.
@ast
Requirement of multiple cis-ac ...... ne expression and replication.
@en
Requirement of multiple cis-ac ...... ne expression and replication.
@nl
P2093
P2860
P1433
P1476
Requirement of multiple cis-ac ...... ne expression and replication.
@en
P2093
James J McCoy
Jeffery L Meier
Michael J Keller
P2860
P304
P356
10.1128/JVI.76.1.313-326.2002
P407
P577
2002-01-01T00:00:00Z