Intramolecular epistasis and the evolution of a new enzymatic function
about
Cyanuric acid hydrolase: evolutionary innovation by structural concatenationVestigialization of an Allosteric Switch: Genetic and Structural Mechanisms for the Evolution of Constitutive Activity in a Steroid Hormone ReceptorThe structure of the hexameric atrazine chlorohydrolase AtzAX-ray structure of the amidase domain of AtzF, the allophanate hydrolase from the cyanuric acid-mineralizing multienzyme complex.Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron.Expanding the enzyme universe: accessing non-natural reactions by mechanism-guided directed evolution.Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native ActivitySubstrate ambiguous enzymes within the Escherichia coli proteome offer different evolutionary solutions to the same problem.Evolution of atrazine-degrading capabilities in the environment.Dynamics and constraints of enzyme evolution.Stepwise enhancement of catalytic performance of haloalkane dehalogenase LinB towards β-hexachlorocyclohexane.How mutational epistasis impairs predictability in protein evolution and designOngoing functional evolution of the bacterial atrazine chlorohydrolase AtzA.Constrained evolution of a bispecific enzyme: lessons for biocatalyst design.Expanded insecticide catabolic activity gained by a single nucleotide substitution in a bacterial carbamate hydrolase gene.Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction
P2860
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P2860
Intramolecular epistasis and the evolution of a new enzymatic function
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Intramolecular epistasis and the evolution of a new enzymatic function
@ast
Intramolecular epistasis and the evolution of a new enzymatic function
@en
Intramolecular epistasis and the evolution of a new enzymatic function
@nl
type
label
Intramolecular epistasis and the evolution of a new enzymatic function
@ast
Intramolecular epistasis and the evolution of a new enzymatic function
@en
Intramolecular epistasis and the evolution of a new enzymatic function
@nl
prefLabel
Intramolecular epistasis and the evolution of a new enzymatic function
@ast
Intramolecular epistasis and the evolution of a new enzymatic function
@en
Intramolecular epistasis and the evolution of a new enzymatic function
@nl
P2860
P50
P1433
P1476
Intramolecular epistasis and the evolution of a new enzymatic function
@en
P2093
Robyn J Russell
Sajid Noor
P2860
P304
P356
10.1371/JOURNAL.PONE.0039822
P407
P577
2012-06-29T00:00:00Z