The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.
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Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodiesBY55 monoclonal antibody delineates within human cord blood and bone marrow lymphocytes distinct cell subsets mediating cytotoxic activityThe integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transductionCytogenetic abnormalities in natural killer cell lymphoma/leukaemia--is there a consistent pattern?Blockade of the interleukin-2 receptor by anti-Tac antibody inhibits the generation of antigen-nonspecific suppressor T cells in vitro.Generation of lymphokine-activated killer cells: synergy between tumor necrosis factor and interleukin 2Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor.Chimeric cytotoxin IL2-PE40 delays and mitigates adjuvant-induced arthritis in rats.Murine interleukin 2 receptor beta chain: dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertionProduction of granulocyte/macrophage-colony-stimulating factor by human natural killer cells. Modulation by the p75 subunit of the interleukin 2 receptor and by the CD2 receptor.Suppression of interleukin 2-dependent human T cell growth in vitro by prostaglandin E (PGE) and their precursor fatty acids. Evidence for a PGE-independent mechanism of inhibition by the fatty acidsPreclinical and phase I clinical trial of blockade of IL-15 using Mikbeta1 monoclonal antibody in T cell large granular lymphocyte leukemiaThe contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseasesRole of common-gamma chain cytokines in NK cell development and function: perspectives for immunotherapy.The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cellsThe clinical immunobiology of interleukin-2: potential modified uses for improved cancer treatmentHuman NK cells in health and disease: clinical, functional, phenotypic and DNA genotypic characteristics.Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donorsResponse of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF.Interleukin 2-induced proliferation of murine natural killer cells in vivo.Cyclosporin A inhibition of interleukin 2 gene expression, but not natural killer cell proliferation, after interferon induction in vivo.Functional consequences of interleukin 2 receptor expression on resting human lymphocytes. Identification of a novel natural killer cell subset with high affinity receptorsIncreased expression of the interleukin 2 (IL-2) receptor beta chain (p70) on CD56+ natural killer cells after in vivo IL-2 therapy: p70 expression does not alone predict the level of intermediate affinity IL-2 binding.Interaction of Fc receptor (CD16) ligands induces transcription of interleukin 2 receptor (CD25) and lymphokine genes and expression of their products in human natural killer cells.Studies of lymphokine-activated killer (LAK) cells. I. Evidence using novel monoclonal antibodies that most human LAK precursor cells share a common surface marker.Characterization of the human interleukin-2 receptor beta-chain gene promoter: regulation of promoter activity by ets gene productsThe interleukin 2 receptor (IL-2R): the IL-2R alpha subunit alters the function of the IL-2R beta subunit to enhance IL-2 binding and signaling by mechanisms that do not require binding of IL-2 to IL-2R alpha subunit.Localization in human interleukin 2 of the binding site to the alpha chain (p55) of the interleukin 2 receptorCombination strategies to enhance antitumor ADCC.The human interleukin-2 receptor. Recent studies of structure and regulation.Lymphokine-activated killer cells. Induction and function.Expression of novel interleukin 2 binding molecules and their functional roles in human B cell differentiation.Cytokines and their role as growth factors and in regulation of immune responses.Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck.Induction by interleukin-15 of human killer cell activity against lung cancer cell lines and its regulatory mechanisms.Quantitation of IL-2Rp75 (CD122) expression on mononuclear cells in rheumatic disease.Mutation of Asp20 of human interleukin-2 reveals a dual role of the p55 alpha chain of the interleukin-2 receptor.Interleukin 2 receptors on squamous cell carcinomas of the head and neck. Characterization and functional role.Two distinct P70 interleukin-2 receptors on a murine large granular lymphocyte clone Y479.Activation of natural killer cells via the p75 interleukin 2 receptor.
P2860
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P2860
The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.
description
1987 nî lūn-bûn
@nan
1987 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
The p75 peptide is the recepto ...... n 2 activation of these cells.
@ast
The p75 peptide is the recepto ...... n 2 activation of these cells.
@en
The p75 peptide is the recepto ...... n 2 activation of these cells.
@nl
type
label
The p75 peptide is the recepto ...... n 2 activation of these cells.
@ast
The p75 peptide is the recepto ...... n 2 activation of these cells.
@en
The p75 peptide is the recepto ...... n 2 activation of these cells.
@nl
prefLabel
The p75 peptide is the recepto ...... n 2 activation of these cells.
@ast
The p75 peptide is the recepto ...... n 2 activation of these cells.
@en
The p75 peptide is the recepto ...... n 2 activation of these cells.
@nl
P2093
P2860
P356
P1476
The p75 peptide is the recepto ...... n 2 activation of these cells.
@en
P2093
Bongiovanni KF
Goldman CK
Waldmann TA
P2860
P304
P356
10.1073/PNAS.84.15.5394
P407
P577
1987-08-01T00:00:00Z