Foamy virus vector integration sites in normal human cells
about
Mouse mammary tumor virus integration site selection in human and mouse genomesLEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integrationProgresses towards safe and efficient gene therapy vectorsFoamy virus vectors for HIV gene therapyFoamy virus biology and its application for vector developmentHematopoietic stem cell engineering at a crossroadsGene therapy studies in a canine model of X-linked severe combined immunodeficiencyFunctional and structural characterization of the integrase from the prototype foamy virusThe mechanism of retroviral integration from X-ray structures of its key intermediatesAltering murine leukemia virus integration through disruption of the integrase and BET protein family interactionGenome editing: the road of CRISPR/Cas9 from bench to clinicIdentifying Cancer Driver Genes Using Replication-Incompetent Retroviral VectorsMolecular ecology and natural history of simian foamy virus infection in wild-living chimpanzeesRetroviral DNA IntegrationSelection of target sites for mobile DNA integration in the human genomeStructural and sequencing analysis of local target DNA recognition by MLV integrase.No evidence of clonal dominance after transplant of HOXB4-expanded cord blood cells in a nonhuman primate model.Intravenous injection of a foamy virus vector to correct canine SCID-X1.Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integrationGene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vectorHTLV-1 integration into transcriptionally active genomic regions is associated with proviral expression and with HAM/TSPThe lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication.Integration site selection by retroviral vectors: molecular mechanism and clinical consequences.Foamy virus vector-mediated gene correction of a mouse model of Wiskott-Aldrich syndrome.Concise review: lessons learned from clinical trials of gene therapy in monogenic immunodeficiency diseases.Specific insertions of zinc finger domains into Gag-Pol yield engineered retroviral vectors with selective integration propertiesThe foamy virus genome remains unintegrated in the nuclei of G1/S phase-arrested cells, and integrase is critical for preintegration complex transport into the nucleus.Foamy and lentiviral vectors transduce canine long-term repopulating cells at similar efficiency.Structural basis for spumavirus GAG tethering to chromatinDeciphering the code for retroviral integration target site selectionMouse mammary tumor virus-based vector transduces non-dividing cells, enters the nucleus via a TNPO3-independent pathway and integrates in a less biased fashion than other retroviruses.Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular diseaseTranscriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration siteStem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency.Tracking of specific integrant clones in dogs treated with foamy virus vectors.Integration site preference of xenotropic murine leukemia virus-related virus, a new human retrovirus associated with prostate cancer.Treatment of canine leukocyte adhesion deficiency by foamy virus vectors expressing CD18 from a PGK promoter.Integration site choice of a feline immunodeficiency virus vector.Porcine endogenous retrovirus integration sites in the human genome: features in common with those of murine leukemia virus
P2860
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P2860
Foamy virus vector integration sites in normal human cells
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Foamy virus vector integration sites in normal human cells
@ast
Foamy virus vector integration sites in normal human cells
@en
Foamy virus vector integration sites in normal human cells
@nl
type
label
Foamy virus vector integration sites in normal human cells
@ast
Foamy virus vector integration sites in normal human cells
@en
Foamy virus vector integration sites in normal human cells
@nl
prefLabel
Foamy virus vector integration sites in normal human cells
@ast
Foamy virus vector integration sites in normal human cells
@en
Foamy virus vector integration sites in normal human cells
@nl
P2093
P2860
P356
P1476
Foamy virus vector integration sites in normal human cells
@en
P2093
Grant D Trobridge
Hans-Peter Kiem
James M Allen
Michael A Jacobs
Rajinder Kaul
P2860
P304
P356
10.1073/PNAS.0510046103
P407
P577
2006-01-20T00:00:00Z