Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia
about
The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodiesTGF-β - an excellent servant but a bad masterTargeting the adaptability of heterogeneous aneuploidsDeletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma.The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia.Inhibition of the intrinsic but not the extrinsic apoptosis pathway accelerates and drives MYC-driven tumorigenesis towards acute myeloid leukemia.Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.SNP array analysis of acute promyelocytic leukemia may be of prognostic relevance and identifies a potential high risk group with recurrent deletions on chromosomal subband 1q31.3.MYC protein expression in primary diffuse large B-cell lymphoma of the central nervous systemDirect and indirect targeting of MYC to treat acute myeloid leukemiaTreatment-influenced associations of PML-RARα mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia.Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia.PML-RARα co-operates with Sox4 in acute myeloid leukemia development in miceTruncated form of TGF-βRII, but not its absence, induces memory CD8+ T cell expansion and lymphoproliferative disorder in mice.Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA.C2ORF40 suppresses breast cancer cell proliferation and invasion through modulating expression of M phase cell cycle genes.Notch signaling in acute promyelocytic leukemiaNew insights into the troubles of aneuploidyTribbles in disease: Signaling pathways important for cellular function and neoplastic transformation.Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leapGene copy-number alterations: a cost-benefit analysis.PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.Pathways related to PMA-differentiated THP1 human monocytic leukemia cells revealed by RNA-Seq.Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.The importance of molecular cytogenetic analysis prior to using cell lines in research: The case of the KG-1a leukemia cell line.Targeting pseudokinase TRIB3 brings about a new therapeutic option for acute promyelocytic leukemia.Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia.
P2860
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P2860
Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia
description
2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@ast
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@en
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@nl
type
label
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@ast
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@en
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@nl
prefLabel
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@ast
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@en
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@nl
P2093
P2860
P356
P1476
Gain of MYC underlies recurren ...... n acute promyelocytic leukemia
@en
P2093
Angell Shieh
George Zhu
Guangwei Wei
Jasmine C Y Wong
Joshua Dubansky
Kevin M Shannon
Letetia Jones
Mei Lin Maunakea
Michelle M Le Beau
P2860
P304
P356
10.1084/JEM.20091071
P407
P577
2010-11-08T00:00:00Z