Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway.
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The Modulation of Apoptotic Pathways by GammaherpesvirusesEmerging therapeutic strategies for Epstein-Barr virus+ post-transplant lymphoproliferative disorderEpstein-Barr virus and the origin of Hodgkin lymphomaRoles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implicationsProtein kinase inhibitors against malignant lymphomaEpstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic miceActivation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication.Host-Cell Survival and Death During Chlamydia InfectionEpstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma.Epstein-Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: implications for viral persistence and intrathecal B-cell activation.LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells.EBV LMP2A provides a surrogate pre-B cell receptor signal through constitutive activation of the ERK/MAPK pathway.Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A.Epstein-Barr virus in Burkitt's lymphoma: a role for latent membrane protein 2AEpstein-Barr virus LMP2A alters in vivo and in vitro models of B-cell anergy, but not deletion, in response to autoantigen.Human Cytomegalovirus Latency: Approaching the Gordian Knot.Developments in Burkitt's lymphoma: novel cooperations in oncogenic MYC signaling.Human viruses and cancer.The effect of Epstein-Barr virus Latent Membrane Protein 2 expression on the kinetics of early B cell infectionProtein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1The role of Epstein-Barr virus in cancer.Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer.Epstein-Barr virus LMP2A enhances B-cell responses in vivo and in vitroEpstein-Barr virus LMP2A imposes sensitivity to apoptosis.Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma.Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomasEBV-driven B-cell lymphoproliferative disorders: from biology, classification and differential diagnosis to clinical management.LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis.Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+ (EBV+) B cell lymphomas.The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedsideA shared gene expression signature in mouse models of EBV-associated and non-EBV-associated Burkitt lymphomaEpstein-barr virus latent membrane protein 2B (LMP2B) modulates LMP2A activity.BH3 Profiling Reveals Selectivity by Herpesviruses for Specific Bcl-2 Proteins To Mediate Survival of Latently Infected Cells.K1 and K15 of Kaposi's Sarcoma-Associated Herpesvirus Are Partial Functional Homologues of Latent Membrane Protein 2A of Epstein-Barr Virus.Distinct Viral and Mutational Spectrum of Endemic Burkitt Lymphoma.Primary CD4+ T-cell responses provide both helper and cytotoxic functions during Epstein-Barr virus infection and transformation of fetal cord blood B cellsEpstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model.Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway.Epstein-Barr virus latent membrane protein 2A exacerbates experimental autoimmune encephalomyelitis and enhances antigen presentation function.Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells
P2860
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P2860
Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Epstein-Barr virus (EBV) LMP2A ...... n of the Ras/PI3K/Akt pathway.
@ast
Epstein-Barr virus (EBV) LMP2A ...... n of the Ras/PI3K/Akt pathway.
@en
type
label
Epstein-Barr virus (EBV) LMP2A ...... n of the Ras/PI3K/Akt pathway.
@ast
Epstein-Barr virus (EBV) LMP2A ...... n of the Ras/PI3K/Akt pathway.
@en
prefLabel
Epstein-Barr virus (EBV) LMP2A ...... n of the Ras/PI3K/Akt pathway.
@ast
Epstein-Barr virus (EBV) LMP2A ...... n of the Ras/PI3K/Akt pathway.
@en
P2860
P356
P1433
P1476
Epstein-Barr virus (EBV) LMP2A ...... n of the Ras/PI3K/Akt pathway.
@en
P2093
Richard Longnecker
Toni Portis
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207905
P407
P577
2004-11-01T00:00:00Z
P5875
P6179
1012159223