The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo
about
Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling moduleActivation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane proteinEmerging therapeutic strategies for Epstein-Barr virus+ post-transplant lymphoproliferative disorderEpstein-Barr Virus: Diseases Linked to Infection and TransformationMulti-transmembrane protein K15 of Kaposi's sarcoma-associated herpesvirus targets Lyn kinase in the membrane raft and induces NFAT/AP1 activities.Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signalEpstein-Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: implications for viral persistence and intrathecal B-cell activation.Roles of the ITAM and PY motifs of Epstein-Barr virus latent membrane protein 2A in the inhibition of epithelial cell differentiation and activation of {beta}-catenin signalingEpstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway.Epstein-Barr virus LMP2A interferes with global transcription factor regulation when expressed during B-lymphocyte development.ITAMs versus ITIMs: striking a balance during cell regulation.Adapters in lymphocyte signalingThe effect of Epstein-Barr virus Latent Membrane Protein 2 expression on the kinetics of early B cell infectionThe effects of the Epstein-Barr virus latent membrane protein 2A on B cell function.Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer.Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma.Itchy, a Nedd4 ubiquitin ligase, downregulates latent membrane protein 2A activity in B-cell signaling.The ITAM in Nef influences acute pathogenesis of AIDS-inducing simian immunodeficiency viruses SIVsm and SIVagm without altering kinetics or extent of viremiaAn immunoreceptor tyrosine activation motif in the mouse mammary tumor virus envelope protein plays a role in virus-induced mammary tumors.Subversion of B lymphocyte signaling by infectious agents.Epstein-Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors.Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+ (EBV+) B cell lymphomas.K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosisEpstein-Barr virus latent membrane protein 2A exacerbates experimental autoimmune encephalomyelitis and enhances antigen presentation function.Dasatinib therapy results in decreased B cell proliferation, splenomegaly, and tumor growth in a murine model of lymphoma expressing Myc and Epstein-Barr virus LMP2A.Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A.Mechanisms of B-cell lymphoma pathogenesis.Epstein-Barr virus Latent Membrane Protein 2A (LMP2A)-mediated changes in Fas expression and Fas-dependent apoptosis: Role of Lyn/Syk activation.Role of ITAM-containing adapter proteins and their receptors in the immune system and bone.Mouse mammary tumor virus suppresses apoptosis of mammary epithelial cells through ITAM-mediated signaling.ITAM-mediated tonic signalling through pre-BCR and BCR complexes.EBV LMP2A affects LMP1-mediated NF-kappaB signaling and survival of lymphoma cells by regulating TRAF2 expression.An auto-regulatory loop for EBV LMP2A involves activation of Notch.Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase LynTonic B-cell and viral ITAM signaling: context is everything.Epstein-Barr virus latent membrane protein 2A exploits Notch1 to alter B-cell identity in vivo.NF-κB as a target for oncogenic viruses.The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling.LMP2A does not require palmitoylation to localize to buoyant complexes or for function.Human viral oncogenesis: a cancer hallmarks analysis
P2860
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P2860
The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
The LMP2A ITAM is essential fo ...... t and survival signals in vivo
@ast
The LMP2A ITAM is essential fo ...... t and survival signals in vivo
@en
type
label
The LMP2A ITAM is essential fo ...... t and survival signals in vivo
@ast
The LMP2A ITAM is essential fo ...... t and survival signals in vivo
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prefLabel
The LMP2A ITAM is essential fo ...... t and survival signals in vivo
@ast
The LMP2A ITAM is essential fo ...... t and survival signals in vivo
@en
P2860
P1433
P1476
The LMP2A ITAM is essential fo ...... t and survival signals in vivo
@en
P2093
R G Caldwell
R Longnecker
P2860
P304
P356
10.1128/JVI.74.19.9115-9124.2000
P577
2000-10-01T00:00:00Z