TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells. - Wikidata - wikimedia - TriplyDB

TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.

TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.

http://www.wikidata.org/entity/Q34352727

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The secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators Heparan sulfate signaling in cancer SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.The differential spatiotemporal expression pattern of shelterin genes throughout lifespan ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2.A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.Over-expression of telomere binding factors (TRF1 & TRF2) in renal cell carcinoma and their inhibition by using SiRNA induce apoptosis, reduce cell proliferation and migration invitro.TeloPIN: a database of telomeric proteins interaction network in mammalian cells Balancing the innate immune system in tumor development.New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape The topoisomerase II catalytic inhibitor ICRF-193 preferentially targets telomeres that are capped by TRF2.Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.A higher-order entity formed by the flexible assembly of RAP1 with TRF2.TRF2 acts as a transcriptional regulator in tumor angiogenesis.High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses.Heparan sulfation is essential for the prevention of cellular senescence.Telomeric repeat-binding factor 2: a marker for survival and anti-EGFR efficacy in oral carcinoma A novel pathway links telomeres to NK-cell activity: Implications for immunotherapy The c-Jun N-terminal kinase prevents oxidative stress induced by UV and thermal stresses in corals and human cells.Telomeric impact of conventional chemotherapy.Transcriptional outcome of telomere signalling.Cellular senescence: from growth arrest to immunogenic conversion.Disruption of direct 3D telomere-TRF2 interaction through two molecularly disparate mechanisms is a hallmark of primary Hodgkin and Reed-Sternberg cells.The long and the short of TRF2 in neurogenesis.Telomere-driven diseases and telomere-targeting therapies.Rare germline alterations in cancer-related genes associated with the risk of multiple primary tumor development.Transcription regulation of CDKN1A (p21/CIP1/WAF1) by TRF2 is epigenetically controlled through the REST repressor complex.Validation of commercial ERK antibodies against the ERK orthologue of the scleractinian coral Stylophora pistillata Differential senescence capacities in meibomian gland carcinoma and basal cell carcinoma.Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites.Tailoring Natural Killer cell immunotherapy to the tumour microenvironment.The heparan sulfate 3-O-sulfotransferases (HS3ST) 2, 3B and 4 enhance proliferation and survival in breast cancer MDA-MB-231 cells.The Wilms' tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression.DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands.p38 MAPK pathway and its interaction with TRF2 in cisplatin induced chemotherapeutic response in head and neck cancer.Stem and immune cells in colorectal primary tumour: Number and function of subsets may diagnose metastasis The Pro-Tumoral Activity of Heparan Sulfate 3--Sulfotransferase 3B (HS3ST3B) in Breast Cancer MDA-MB-231 Cells Is Dependent on the Expression of Neuropilin-1 Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression

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TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.

http://www.wikidata.org/entity/Q34352727

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

@ast

TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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type

label

TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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prefLabel

TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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Nature Cell Biology

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TRF2 inhibits a cell-extrinsic ...... cells eliminate cancer cells.

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Aaron Mendez-Bermudez

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Adeline Augereau

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Béatrice Horard

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Claire T'kint de Rodenbeeke

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Céline Cognet

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Daniel Peeper

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Delphine Poncet

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Els Verhoeyen

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Eric Gilson

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Florian Lépinasse

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P2860

Mammalian telomeres end in a large duplex loop

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

In vivo stoichiometry of shelterin components

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

The Vienna classification of gastrointestinal epithelial neoplasia

Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

TRF2 Protects Human Telomeres from End-to-End Fusions

Creation of human tumour cells with defined genetic elements

Shelterin: the protein complex that shapes and safeguards human telomeres

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10.1038/NCB2774

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7

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15

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François-Loïc Cosset

Annamaria Biroccio

Jacqueline Marvel

Jean-Yves Scoazec

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2013-06-23T00:00:00Z

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241692973

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1000559822

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23792691

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