Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner
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Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to IntegrationFunctional evidence for the involvement of microtubules and dynein motor complexes in TRIM5α-mediated restriction of retroviruses.SUMO-interacting motifs of human TRIM5α are important for antiviral activityA novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screenArsenic exposure and prevalence of the varicella zoster virus in the United States: NHANES (2003-2004 and 2009-2010)TRIM5 structure, HIV-1 capsid recognition, and innate immune signalingPreclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 TransgeneIdentification of an arsenic-sensitive block to primate lentiviral infection of human dendritic cells.TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling.The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion.Arsenic trioxide stabilizes accumulations of adeno-associated virus virions at the perinuclear region, increasing transduction in vitro and in vivo.A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restrictionAn invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding.Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human componentsCaging the beast: TRIM5α binding to the HIV-1 core.Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell LinesBoth TRIM5alpha and TRIMCyp have only weak antiviral activity in canine D17 cells.The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import.TRIM5alpha and TRIMCyp form apparent hexamers and their multimeric state is not affected by exposure to restriction-sensitive viruses or by treatment with pharmacological inhibitors.Arsenic modulates APOBEC3G-mediated restriction to HIV-1 infection in myeloid dendritic cells.
P2860
Q28546614-30766DC9-7C51-477C-966C-45C2DF9E4058Q33602830-83C825C3-A89D-4082-BE11-0CA14D267835Q33872238-953D43EC-F3B4-4B2D-9B77-2C9C395BF59FQ34565670-248B0F96-B55D-4557-89C0-30C1B109DEC6Q35683263-DD26B67D-A16F-492C-9A61-E4AB4E52EBD9Q35878245-D9992188-EC63-43F9-9A78-2E5538F2B228Q36242630-79CB6E1F-D2D6-4675-BFCB-AD967029B634Q36315023-382BD9B0-4994-4145-BE1A-5A6D22EB599EQ36433878-7138FAD3-F394-4426-BC7C-76D144A97B89Q36714770-99339E8F-DFE1-4ECF-95C8-6D31D12C15E4Q36760126-902EC945-074A-4A3B-8E0C-ECCD0B4124C4Q37096418-2F1724AC-ED59-461E-9516-CBF08E61B280Q37127998-8789586A-2E33-4378-92BE-8320CE4056DAQ37363070-54C20A67-265F-475B-AB1F-3A2E3657E765Q38618179-83224D83-2FBF-4314-9373-0B9948DC934DQ38698793-20BD1A7E-1280-4F7E-9C0D-F636E08AE9C7Q38927893-4825A0B3-AAE6-4515-A451-2EF39C90D141Q39187298-5F2125BE-C610-4647-932B-5835344012C4Q39779626-18F67603-221B-4B85-8A71-530D686470E4Q42921091-92827B60-1A6B-4041-872F-7C1B1CFF6FB9
P2860
Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner
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2006 nî lūn-bûn
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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2006 թվականի փետրվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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Arsenic counteracts human immu ...... n a cell type-dependent manner
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Arsenic counteracts human immu ...... n a cell type-dependent manner
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Arsenic counteracts human immu ...... n a cell type-dependent manner
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label
Arsenic counteracts human immu ...... n a cell type-dependent manner
@ast
Arsenic counteracts human immu ...... n a cell type-dependent manner
@en
Arsenic counteracts human immu ...... n a cell type-dependent manner
@nl
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Arsenic counteracts human immu ...... n a cell type-dependent manner
@ast
Arsenic counteracts human immu ...... n a cell type-dependent manner
@en
Arsenic counteracts human immu ...... n a cell type-dependent manner
@nl
P2860
P1433
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Arsenic counteracts human immu ...... n a cell type-dependent manner
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P2093
Elena Sokolskaja
Sarah Sebastian
P2860
P304
P356
10.1128/JVI.80.4.2051-2054.2006
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P50
P577
2006-02-01T00:00:00Z