The role of neurosteroids and nongenomic effects of progestins in the ventral tegmental area in mediating sexual receptivity of rodents.
about
Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor.Neurosteroids' effects and mechanisms for social, cognitive, emotional, and physical functionsInhibiting biosynthesis and/or metabolism of progestins in the ventral tegmental area attenuates lordosis of rats in behavioural oestrusFemale mice with deletion of Type One 5α-reductase have reduced reproductive responding during proestrus and after hormone-primingMembrane progesterone receptor expression in mammalian tissues: a review of regulation and physiological implications.A new look at the 5alpha-reductase inhibitor finasteride.Divergent mechanisms for trophic actions of estrogens in the brain and peripheral tissues.Novel substrates for, and sources of, progestogens for reproduction.Serotonin in microdialysate from the mediobasal hypothalamus increases after progesterone administration to estrogen primed macaques.Effects and Mechanisms of 3α,5α,-THP on Emotion, Motivation, and Reward Functions Involving Pregnane Xenobiotic Receptor.Progesterone can enhance consolidation and/or performance in spatial, object and working memory tasks in Long-Evans rats.Progesterone-facilitated lordosis of estradiol-primed mice is attenuated by knocking down expression of membrane progestin receptors in the midbrain.Membrane progestin receptors in the midbrain ventral tegmental area are required for progesterone-facilitated lordosis of ratsRole of progestins with partial antiandrogenic effects.Progestins influence motivation, reward, conditioning, stress, and/or response to drugs of abuse.6-hydroxydopamine lesions enhance progesterone-facilitated lordosis of rats and hamsters, independent of effects on motor behavior.Progestin concentrations are increased following paced mating in midbrain, hippocampus, diencephalon, and cortex of rats in behavioral estrus, but only in midbrain of diestrous ratsEffects of manipulating progesterone and NMDA receptors in the ventral tegmental area for lordosis of hamsters and rats.MK-801 infusions to the ventral tegmental area and ventromedial hypothalamus produce opposite effects on lordosis of hormone-primed ratsMembrane actions of progestins at dopamine type 1-like and GABAA receptors involve downstream signal transduction pathways.Activity of protein kinase C is important for 3alpha,5alpha-THP's actions at dopamine type 1-like and/or GABAA receptors in the ventral tegmental area for lordosis of rats.Increasing 3alpha,5alpha-THP following inhibition of neurosteroid biosynthesis in the ventral tegmental area reinstates anti-anxiety, social, and sexual behavior of naturally receptive rats.Brain levels of prostaglandins, endocannabinoids, and related lipids are affected by mating strategies.Oxytocin and/or steroid hormone binding globulin infused into the ventral tegmental area modulates progestogen-mediated lordosis.Infusions of anti-sense oligonucleotides for DARPP-32 to the ventral tegmental area reduce effects of progesterone- and a dopamine type 1-like receptor agonist to facilitate lordosis.Pregnane xenobiotic receptors and membrane progestin receptors: role in neurosteroid-mediated motivated behavioursNovel receptor targets for production and action of allopregnanolone in the central nervous system: a focus on pregnane xenobiotic receptorThe pregnane xenobiotic receptor, a prominent liver factor, has actions in the midbrain for neurosteroid synthesis and behavioral/neural plasticity of female rats.Progestogens influence cognitive processes in aging.Inhibiting progesterone metabolism in the hippocampus of rats in behavioral estrus decreases anxiolytic behaviors and enhances exploratory and antinociceptive behaviors.Ventral tegmental area infusions of inhibitors of the biosynthesis and metabolism of 3alpha,5alpha-THP attenuate lordosis of hormone-primed and behavioural oestrous rats and hamsters.In the ventral tegmental area, G-proteins and cAMP mediate the neurosteroid 3alpha,5alpha-THP's actions at dopamine type 1 receptors for lordosis of rats.In the ventral tegmental area, progestins' membrane-mediated actions for lordosis of hamsters and rats involve protein kinase A.Infusions of 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) to the ventral tegmental area, but not the substantia nigra, enhance exploratory, anti-anxiety, social and sexual behaviours and concomitantly increase 3alpha,5alpha-THP concentrationsIn the ventral tegmental area, cyclic AMP mediates the actions of progesterone at dopamine type 1 receptors for lordosis of rats and hamsters.Sigma-1 receptor knockout impairs neurogenesis in dentate gyrus of adult hippocampus via down-regulation of NMDA receptors.
P2860
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P2860
The role of neurosteroids and nongenomic effects of progestins in the ventral tegmental area in mediating sexual receptivity of rodents.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The role of neurosteroids and ...... sexual receptivity of rodents.
@ast
The role of neurosteroids and ...... sexual receptivity of rodents.
@en
The role of neurosteroids and ...... sexual receptivity of rodents.
@nl
type
label
The role of neurosteroids and ...... sexual receptivity of rodents.
@ast
The role of neurosteroids and ...... sexual receptivity of rodents.
@en
The role of neurosteroids and ...... sexual receptivity of rodents.
@nl
prefLabel
The role of neurosteroids and ...... sexual receptivity of rodents.
@ast
The role of neurosteroids and ...... sexual receptivity of rodents.
@en
The role of neurosteroids and ...... sexual receptivity of rodents.
@nl
P356
P1476
The role of neurosteroids and ...... sexual receptivity of rodents.
@en
P2093
P304
P356
10.1006/HBEH.2001.1674
P577
2001-09-01T00:00:00Z