R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis.
about
RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovaryHuman RSPO1/R-spondin1 is expressed during early ovary development and augments β-catenin signalingR-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activationR-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signalingMouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expressionZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive mannerLGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressorInteraction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondinLGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signalingCoat variation in the domestic dog is governed by variants in three genesWnt/beta-catenin signaling: components, mechanisms, and diseasesWnt signal transduction pathwaysWnt signaling: the good and the badControl of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in CancerLGR4 and Its Role in Intestinal Protection and Energy MetabolismKeeping Wnt signalosome in check by vesicular trafficAdult mammalian stem cells: the role of Wnt, Lgr5 and R-spondinsThe R-spondin protein familyCellular signaling and biological functions of R-spondinsThe structural basis of R-spondin recognition by LGR5 and RNF43Structural basis for R-spondin recognition by LGR4/5/6 receptorsCrystal Structures of Lgr4 and Its Complex with R-Spondin1Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondinDistinct transcriptional networks in quiescent myoblasts: a role for Wnt signaling in reversible vs. irreversible arrestDifferentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophyRecombinant R-spondin2 and Wnt3a up- and down-regulate novel target genes in C57MG mouse mammary epithelial cellsWnt11 promotes osteoblast maturation and mineralization through R-spondin 2Lmx1a encodes a rostral set of mesodiencephalic dopaminergic neurons marked by the Wnt/B-catenin signaling activator R-spondin 2Man's best friend becomes biology's best in show: genome analyses in the domestic dogN-Glycosylation of Human R-Spondin 1 Is Required for Efficient Secretion and Stability but Not for Its Heparin Binding AbilityCrystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).Wnt proteins.Integrated Biophysical and Biochemical Signals Augment Megakaryopoiesis and Thrombopoiesis in a Three-Dimensional Rotary Culture System.R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation.Cloning and expression of R-Spondin1 in different vertebrates suggests a conserved role in ovarian developmentLrp4 modulates extracellular integration of cell signaling pathways in development.Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function.To beta or not to beta: canonical beta-catenin signaling pathway and ovarian development
P2860
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P2860
R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis.
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@ast
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@en
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@nl
type
label
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@ast
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@en
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@nl
prefLabel
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@ast
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@en
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@nl
P2093
P1433
P1476
R-Spondin2 is a secreted activ ...... quired for Xenopus myogenesis.
@en
P2093
Andrei Glinka
Christof Niehrs
Ivan del Barco Barrantes
Olga Kazanskaya
Peter Stannek
P304
P356
10.1016/J.DEVCEL.2004.07.019
P407
P577
2004-10-01T00:00:00Z