Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis. - Wikidata - wikimedia - TriplyDB

Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.

Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.

http://www.wikidata.org/entity/Q34359198

about

Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype Chemopreventive drugs: mechanisms via inhibition of cancer stem cells in colorectal cancer The evolving role of nonsteroidal anti-inflammatory drugs in colon cancer prevention: a cause for optimism Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells.Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.Preoperative low dose NSAID treatment influences the genes for stemness, growth, invasion and metastasis in colorectal cancer.Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin.BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs.Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1.PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.Non-cell autonomous effects of targeting inducible PGE2 synthesis during inflammation-associated colon carcinogenesis Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth Investigation of nuclear nano-morphology marker as a biomarker for cancer risk assessment using a mouse model.Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis Association of stem-like cells in gender-specific chemoprevention against intestinal neoplasia in MIN mouse.Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.The hallmarks of premalignant conditions: a molecular basis for cancer prevention Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts Sulindac inhibits pancreatic carcinogenesis in LSL-KrasG12D-LSL-Trp53R172H-Pdx-1-Cre mice via suppressing aldo-keto reductase family 1B10 (AKR1B10)Role of apoptosis in colon cancer biology, therapy, and prevention Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice.Occult progression by Apc-deficient intestinal crypts as a target for chemoprevention.FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.Differential effects of 2- and 3-series E-prostaglandins on in vitro expansion of Lgr5+ colonic stem cells.Aspirin and colorectal cancer: back to the future.NSAIDs inhibit tumorigenesis, but how?Consumption of Red/Processed Meat and Colorectal Carcinoma: Possible Mechanisms Underlying the Significant Association.Nonsteroidal anti-inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer.Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells.Targeting Bax interaction sites reveals that only homo-oligomerization sites are essential for its activation.Dietary fat and fiber interactively modulate apoptosis and mitochondrial bioenergetic profiles in mouse colon in a site-specific manner.ADAR1 is essential for intestinal homeostasis and stem cell maintenance.An apoptosis-independent role of SMAC in tumor suppression Obesity promotes colonic stem cell expansion during cancer initiation.Colorectal cancer prevention: Immune modulation taking the stage.Targeting p53-dependent stem cell loss for intestinal chemoprotection.An intermittent approach for cancer chemoprevention.NF-κB signaling in cancer stem cells: a promising therapeutic target?Suppression of the NF‑κB signaling pathway in colon cancer cells by the natural compound Riccardin D from Dumortierahirsute.Synergism of co-delivered nanosized antioxidants displayed enhanced anticancer efficacy in human colon cancer cell lines.

P2860

Q26825103-FDC4EABB-D627-4A5D-9D69-64A39C51C474 Q27026428-85F87458-3891-40B9-ABEF-83E3340787DF Q28087427-28169954-B949-47FF-8162-EF822A2E86F8 Q33579079-7238CE76-EFF6-4796-ABA7-41DAE763D467 Q33838524-9F841990-4184-47E5-B959-F34629AB0584 Q34432882-DE7794CB-1F3C-4F8E-BFFF-5CD2B4C73CE1 Q34572166-F88E0471-CA93-400D-8939-6EB45E5697EA Q34581082-D090EFE4-0C11-4E9A-8D6E-6EF82602C0E5 Q34987859-CC70491E-C758-4975-ACF3-16A2A5837C93 Q35249314-C1651B5B-2687-45A5-8103-8BFF76A2359F Q35356004-306D9737-8A50-4E16-9DC1-200D4E013CA5 Q35928707-9ED66D08-9B52-40C7-9B06-2C1F726AB861 Q36056078-2E1B83EB-1166-4CEC-BF52-9F0619A063EC Q36099347-9E6D1D36-4DA4-4F05-98D0-101D148ABD13 Q36570730-6F9C44D8-C3F0-4447-A566-D248A99027E1 Q36604053-A49455BC-771C-4A5A-807B-C7D25DA3DD48 Q36679858-F2643C8A-2B88-4839-9169-E169656F6FF0 Q36752069-9380A09B-131A-4FF5-9527-3C37431B01C4 Q37151656-7211D86C-FDF6-48E1-ACD6-E2306173A36E Q37331465-CBAC60C3-E73C-431D-A761-1BC671F87A42 Q37395807-880D99CD-0A9D-469F-8ACC-F9E2DBAA271E Q37412026-125655D8-5F0D-4818-A5DF-87A35B1CE6AF Q37580764-CDCD61E5-B644-44DE-B3BD-CC2E114E0DBA Q37616063-B2B44FFC-D157-48F7-97B0-7F6A9D58C6CB Q37626475-38049B3C-8175-42C2-B831-F05E9F6D6011 Q38169133-B9D3187C-6D50-4886-8C78-797E636AA8A0 Q38409303-0FE96444-996B-40E9-8D01-F52E85AC8102 Q38448721-BD3DA53B-A95F-4CF6-AB2B-DB8E23D467C0 Q39016335-743F3BE0-D0B7-49D1-8DB4-0AFEC4EF1B77 Q39197893-92D07532-A779-4DB5-88F7-5CDCA932126C Q39775941-A08EFE5D-A7CB-48E2-8D11-8B1F01124E4F Q40289261-DE157AE3-1E16-4D54-B1CD-584521D288C9 Q41998116-42A22E01-1E1D-4FA7-99E8-6B18CED55975 Q42076725-1B8204C4-CB29-46CA-89D8-F22C20878FEB Q49391998-323BAB24-AF25-44C1-B9A4-B7607DC9DA7E Q50045903-1111F9D9-EF64-4E20-A664-81A65AC97F8F Q51662524-FDE89371-2FB1-4DA1-8AC9-D6D3993DC539 Q52663155-8187783E-A1F3-4C5F-8F70-8C10E0EF0D25 Q52684026-A90EEA34-5EC4-415E-8DC1-1D0031DAD227 Q54943204-D189E4F4-EF20-4B5E-B1EA-05F633455E5A

P2860

Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.

http://www.wikidata.org/entity/Q34359198

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@ast

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@en

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@nl

type

label

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@ast

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@en

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@nl

prefLabel

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@ast

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@en

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@nl

P1433

Q34359198-95205006-233E-47C2-8F3C-C96118076229

P1476

Q34359198-A4E75D93-7E69-4F15-A4C0-150845944BD1

P2093

Q34359198-05BBF4D9-784C-4694-8730-341F0A7B215F

Q34359198-23108C0F-55E3-4C12-93F8-C9B2BB7B6FBF

Q34359198-33D01B1B-5C61-47DD-AF49-FD49CC635F8F

Q34359198-41F0B91E-2C95-40C0-9FFE-73E3C12F166A

Q34359198-50F64758-547E-470D-8348-25BBBC2CD3FA

Q34359198-53C7B652-4D14-44EB-9178-6AAF8E175152

Q34359198-5F458A05-FF29-465E-B7A0-1D3CA1FF9C4C

Q34359198-6BE964F1-431D-4175-B6E7-1A06E6715B8E

Q34359198-877D4A84-A34B-4AA6-8465-D17B3AA0CB59

Q34359198-C14B6B51-6D9D-4660-8820-BF9967BDCBF2

P2860

Q34359198-01A2B283-E0A3-4597-87E5-0B9530376E00

Q34359198-0B225C1B-0EA0-4177-86A5-4B96D63E548F

Q34359198-22DD35EF-ACD7-4E5A-B8A5-146B7813C595

Q34359198-2410CE57-D40D-4443-8E43-FC9AC5C46544

Q34359198-35A8CCEF-AF3B-43CE-A49C-2ADD4D6232A2

Q34359198-3F876BD3-2F23-4B33-9FD1-9E357E029782

Q34359198-443491AA-70E2-4545-9D88-4BFABCFFF777

Q34359198-46EB8AE1-62D1-441A-A5DB-767AC616057C

Q34359198-52C66FA3-D32C-4ADA-9887-F977607B1DD0

Q34359198-562ECFEE-2514-4D77-BE3F-4CE1052788AB

P304

Q34359198-B9B13B4A-8F36-4DD7-84B5-688D8C764D75

P31

Q34359198-59FFEDF2-2D66-48D3-9259-55EE07173671

P356

Q34359198-F5F1E52E-DAA9-40E1-9516-D06084B66F46

P407

Q34359198-5B6E022B-147B-49D8-AF3B-322F23A32F47

P433

Q34359198-80651151-DE5A-4082-B197-CF53FEBF8753

P478

Q34359198-3E426DAC-D2C8-4DCD-93A2-2E63D0CC9026

P577

Q34359198-010B62D8-88E3-497A-82EA-5ABB01008AC8

P5875

Q34359198-9CF80C11-9CE9-4421-A251-027EBCF989B1

P698

Q34359198-378396D3-05D3-4BDA-8455-AF4B9A4F6799

P921

Q34359198-F97D353A-7FF0-4068-B0F5-9CA3F486DED4

P932

Q34359198-88CFF071-697C-4BF2-8CAB-1AC6B1AD623F

P356

PNAS.1010430107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Chemoprevention by nonsteroida ...... via SMAC-dependent apoptosis.

@en

P2093

Brian Leibowitz

http://www.w3.org/2001/XMLSchema#string

Hans Clevers

http://www.w3.org/2001/XMLSchema#string

Hitoshi Okada

http://www.w3.org/2001/XMLSchema#string

Hongtao Liu

http://www.w3.org/2001/XMLSchema#string

Jian Yu

http://www.w3.org/2001/XMLSchema#string

Lin Zhang

http://www.w3.org/2001/XMLSchema#string

Naohide Oue

http://www.w3.org/2001/XMLSchema#string

Nick Barker

http://www.w3.org/2001/XMLSchema#string

Robert E Schoen

http://www.w3.org/2001/XMLSchema#string

Wataru Yasui

http://www.w3.org/2001/XMLSchema#string

P2860

PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome

PTEN-deficient intestinal stem cells initiate intestinal polyposis.

Induced pluripotent stem cell lines derived from human somatic cells

Wnt/beta-catenin signaling in development and disease

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

Identification of stem cells in small intestine and colon by marker gene Lgr5

NSAIDs and chemoprevention

Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues

Cancer genes and the pathways they control

Crypt stem cells as the cells-of-origin of intestinal cancer

P304

20027-20032

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1010430107

http://www.w3.org/2001/XMLSchema#string

P407

P433

46

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P577

2010-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

47644909

http://www.w3.org/2001/XMLSchema#string

P698

21041628

http://www.w3.org/2001/XMLSchema#string

P921

P932

2993406

http://www.w3.org/2001/XMLSchema#string