Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast
about
Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexesAbsence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing.Yeast Edc3 targets RPS28B mRNA for decapping by binding to a 3' untranslated region decay-inducing regulatory element.Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover.Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3pYeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit.Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeastGenetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 proteinNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryInteractions between Upf1 and the decapping factors Edc3 and Pat1 in Saccharomyces cerevisiae.Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway.Telomere length regulation and telomeric chromatin require the nonsense-mediated mRNA decay pathway.Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs.Is there a classical nonsense-mediated decay pathway in trypanosomes?Translational competence of ribosomes released from a premature termination codon is modulated by NMD factors.Overexpression of truncated Nmd3p inhibits protein synthesis in yeast.Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitutionNMD: At the crossroads between translation termination and ribosome recycling.Intra- and intermolecular regulatory interactions in Upf1, the RNA helicase central to nonsense-mediated mRNA decay in yeast.NMD: a multifaceted response to premature translational termination.RNA degradation in Saccharomyces cerevisaeCrystal structure of the UPF2-interacting domain of nonsense-mediated mRNA decay factor UPF1.Nonsense-mediated mRNA decay mutation in Aspergillus nidulans.Aberrant mRNAs with extended 3' UTRs are substrates for rapid degradation by mRNA surveillance.ATP is a cofactor of the Upf1 protein that modulates its translation termination and RNA binding activitiesNonsense-mediated mRNA decay factors cure most [PSI+] prion variants.
P2860
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P2860
Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@ast
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@en
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@nl
type
label
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@ast
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@en
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@nl
prefLabel
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@ast
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@en
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@nl
P2093
P2860
P1433
P1476
Interaction between Nmd2p and ...... ed mRNA decay pathway in yeast
@en
P2093
P2860
P304
P407
P577
1996-02-01T00:00:00Z