Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs. - Wikidata - wikimedia - TriplyDB

Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs.

Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs.

http://www.wikidata.org/entity/Q33967184

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Comparative genomics and evolution of proteins involved in RNA metabolism A 3' UTR sequence stabilizes termination codons in the unspliced RNA of Rous sarcoma virus.Splicing enhances translation in mammalian cells: an additional function of the exon junction complex RNA-binding proteins in neurodegeneration: Seq and you shall receive Absence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing.Scavenger decapping activity facilitates 5' to 3' mRNA decay Identification of a quality-control mechanism for mRNA 5'-end capping.The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae.Targeting of aberrant mRNAs to cytoplasmic processing bodies.Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae Depth of proteome issues: a yeast isotope-coded affinity tag reagent study.Impact of nonsense-mediated mRNA decay on the global expression profile of budding yeast.High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection.5' to 3' mRNA decay factors colocalize with Ty1 gag and human APOBEC3G and promote Ty1 retrotransposition.Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae The code within the code: microRNAs target coding regions.Analysis of the products of mRNA decapping and 3'-to-5' decay by denaturing gel electrophoresis.Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition.The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model A quantitative assay for measuring mRNA decapping by splinted ligation reverse transcription polymerase chain reaction: qSL-RT-PCR Unexpected roles for UPF1 in HIV-1 RNA metabolism and translation.The Upf-dependent decay of wild-type PPR1 mRNA depends on its 5'-UTR and first 92 ORF nucleotides Nonsense-mediated mRNA decay: insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins.Initiation-mediated mRNA decay in yeast affects heat-shock mRNAs, and works through decapping and 5'-to-3' hydrolysis.YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA.Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID).Control of mRNA decapping by positive and negative regulatory elements in the Dcp2 C-terminal domain Telomere cap components influence the rate of senescence in telomerase-deficient yeast cells.Synthetic RNA-protein modules integrated with native translation mechanisms to control gene expression in malaria parasites XRN 5'→3' exoribonucleases: structure, mechanisms and functions.Intra- and intermolecular regulatory interactions in Upf1, the RNA helicase central to nonsense-mediated mRNA decay in yeast.Co-translational mRNA decay in Saccharomyces cerevisiae.Human UPF1 participates in small RNA-induced mRNA downregulation.mRNA quality control pathways in Saccharomyces cerevisiae.The role of disordered protein regions in the assembly of decapping complexes and RNP granules.Regulation of natural mRNAs by the nonsense-mediated mRNA decay pathway.Evidence that XRN4, an Arabidopsis homolog of exoribonuclease XRN1, preferentially impacts transcripts with certain sequences or in particular functional categories.Mechanism, factors, and physiological role of nonsense-mediated mRNA decay.Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila.

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P2860

Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs.

http://www.wikidata.org/entity/Q33967184

description

2001 nî lūn-bûn

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2001 թուականի Մարտին հրատարակուած գիտական յօդուած

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2001 թվականի մարտին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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Upf1p, Nmd2p, and Upf3p regula ...... ing mRNAs and wild-type mRNAs.

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Upf1p, Nmd2p, and Upf3p regula ...... ing mRNAs and wild-type mRNAs.

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Upf1p, Nmd2p, and Upf3p regula ...... ing mRNAs and wild-type mRNAs.

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Upf1p, Nmd2p, and Upf3p regula ...... ing mRNAs and wild-type mRNAs.

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Upf1p, Nmd2p, and Upf3p regula ...... ing mRNAs and wild-type mRNAs.

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MCB.21.5.1515-1530.2001

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Molecular and Cellular Biology

P1476

Upf1p, Nmd2p, and Upf3p regula ...... ing mRNAs and wild-type mRNAs.

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P2093

A Jacobson

http://www.w3.org/2001/XMLSchema#string

F He

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P2860

The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism

The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs

Temperature-sensitive mutations in the Saccharomyces cerevisiae MRT4, GRC5, SLA2 and THS1 genes result in defects in mRNA turnover.

Relationship between yeast polyribosomes and Upf proteins required for nonsense mRNA decay.

NMD3 encodes an essential cytoplasmic protein required for stable 60S ribosomal subunits in Saccharomyces cerevisiae.

The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases

Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover.

Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively

Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen.

A factor required for nonsense-mediated mRNA decay in yeast is exported from the nucleus to the cytoplasm by a nuclear export signal sequence.

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1515-1530

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11238889

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86698

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