Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein. - Wikidata - wikimedia - TriplyDB

Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.

Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.

http://www.wikidata.org/entity/Q34362038

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Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5-based Constructs Recombinant vaccines against T. gondii: comparison between homologous and heterologous vaccination protocols using two viral vectors expressing SAG1 Development of gene therapy to target pancreatic cancer.Novel system uses probasin-based promoter, transcriptional silencers and amplification loop to induce high-level prostate expression A novel method for generating and screening peptides and libraries displayed on adenovirus fiber Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo.A strategy for adenovirus vector targeting with a secreted single chain antibody.Adenoviral vector immunity: its implications and circumvention strategies.Peptide-based technologies to alter adenoviral vector tropism: ways and means for systemic treatment of cancer Effective modifications for improved homologous recombination and high-efficiency generation of recombinant adenovirus-based vectors.Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.Development of a targeted gene vector platform based on simian adenovirus serotype 24.Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxonomy.Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation.An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer.Current strategies and future directions for eluding adenoviral vector immunity Chapter two--Adenovirus strategies for tissue-specific targeting.Avidin-based targeting and purification of a protein IX-modified, metabolically biotinylated adenoviral vector.Transductional targeting of adenovirus vectors for gene therapy Highly specific transgene expression mediated by a complex adenovirus vector incorporating a prostate-specific amplification feedback loop.Metabolic biotinylation of recombinant proteins in mammalian cells and in mice.Oncolytic adenoviruses - selective retargeting to tumor cells.Targeting EGFR with metabolically biotinylated fiber-mosaic adenovirus.A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway Current advances and future challenges in Adenoviral vector biology and targeting Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach.Oncolytic adenovirus retargeted to Delta-EGFR induces selective antiglioma activity In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies.Engineered adenovirus serotypes for overcoming anti-vector immunity.Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors.Capsid-incorporation of antigens into adenovirus capsid proteins for a vaccine approach.CD40-targeted adenoviral cancer vaccines: the long and winding road to the clinic.Tropism-modification strategies for targeted gene delivery using adenoviral vectors.The disulfide bond of an RGD4C motif inserted within the Hi loop of the adenovirus type 5 fiber protein is critical for retargeting to αv -integrins.Improved systemic antitumor therapy with oncolytic adenoviruses by replacing the fiber shaft HSG-binding domain with RGD.Unnatural amino acid incorporation onto adenoviral (Ad) coat proteins facilitates chemoselective modification and retargeting of Ad type 5 vectors.

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Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.

http://www.wikidata.org/entity/Q34362038

description

2002 nî lūn-bûn

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2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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Modulation of adenovirus vecto ...... igands into the fiber protein.

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P356

JVI.76.17.8621-8631.2002

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Journal of Virology

P1476

Modulation of adenovirus vecto ...... igands into the fiber protein.

@en

P2093

Natalya Belousova

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Valentina Krendelchtchikova

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Victor Krasnykh

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P2860

HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

Vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor subtypes in human tumors and their tissues of origin

Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

The mechanism of the growth-inhibitory effect of coxsackie and adenovirus receptor (CAR) on human bladder cancer: a functional analysis of car protein structure.

Recombinant human adenovirus: targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism.

Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector

Genetic targeting of adenoviral vectors.

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8621-8631

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scholarly article

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10.1128/JVI.76.17.8621-8631.2002

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17

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76

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David T. Curiel

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2002-09-01T00:00:00Z

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11222385

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12163581

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136983

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