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Tropism-modification strategies for targeted gene delivery using adenoviral vectors.

Tropism-modification strategies for targeted gene delivery using adenoviral vectors.

http://www.wikidata.org/entity/Q38614156

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New viruses for cancer therapy: meeting clinical needs Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5-based Constructs A short perspective on gene therapy: Clinical experience on gene therapy of gliomablastoma multiforme Circumventing antivector immunity: potential use of nonhuman adenoviral vectors Oncolytic adenovirus-mediated therapy for prostate cancer Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectors Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters Thyroid malignant neoplasm-associated biomarkers as targets for oncolytic virotherapy Development of Adenoviral Delivery Systems to Target Hepatic Stellate Cells In Vivo Cell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interaction A novel capsid-modified oncolytic recombinant adenovirus type 5 for tumor-targeting gene therapy by intravenous route Barriers to inhaled gene therapy of obstructive lung diseases: A review Adenoviral vectors as novel vaccines for influenza.Development of a novel efficient method to construct an adenovirus library displaying random peptides on the fiber knob.Peptide-based technologies to alter adenoviral vector tropism: ways and means for systemic treatment of cancer Oncolytic viruses: From bench to bedside with a focus on safety.Viruses in cancer treatment.Safety profiles and antitumor efficacy of oncolytic adenovirus coated with bioreducible polymer in the treatment of a CAR negative tumor model Mutation in fiber of adenovirus serotype 5 gene therapy vector decreases liver tropism.Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in mice Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery Retargeted oncolytic adenovirus displaying a single variable domain of camelid heavy-chain-only antibody in a fiber protein.A Novel Vaccine Approach for Chagas Disease Using Rare Adenovirus Serotype 48 Vectors.Site-specific gene delivery to stented arteries using magnetically guided zinc oleate-based nanoparticles loaded with adenoviral vectors Evaluation of CD46 re-targeted adenoviral vectors for clinical ovarian cancer intraperitoneal therapy.Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies.An easy method for preparation of Cre-loxP regulated fluorescent adenoviral expression vectors and its application for direct reprogramming into hepatocytes.Human full-length coagulation factor X and a GLA domain-derived 40-mer polypeptide bind to different regions of the adenovirus serotype 5 hexon capsomer.Multiple roles of the coagulation protease cascade during virus infection.Manipulation of adenovirus interactions with host factors for gene therapy applications.Optimization and preclinical design of genetically engineered viruses for human oncolytic therapy.Novel gene delivery systems Adenoviruses as gene/vaccine delivery vectors: promises and pitfalls.Assessment of Specificity of an Adenovirus Targeted to HER3/4.iRGD tumor-penetrating peptide-modified oncolytic adenovirus shows enhanced tumor transduction, intratumoral dissemination and antitumor efficacy.Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses.Getting genetic access to natural adenovirus genomes to explore vector diversity.Effect of Function-Enhanced Mesenchymal Stem Cells Infected With Decorin-Expressing Adenovirus on Hepatic Fibrosis.Exploration of New Sites in Adenovirus Hexon for Foreign Peptides Insertion.

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Tropism-modification strategies for targeted gene delivery using adenoviral vectors.

http://www.wikidata.org/entity/Q38614156

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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2010年學術文章

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2010年學術文章

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name

Tropism-modification strategies for targeted gene delivery using adenoviral vectors.

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type

label

Tropism-modification strategies for targeted gene delivery using adenoviral vectors.

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prefLabel

Tropism-modification strategies for targeted gene delivery using adenoviral vectors.

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Tropism-modification strategies for targeted gene delivery using adenoviral vectors.

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Andrew H Baker

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Angela C Bradshaw

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Raul Alba

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P2860

Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia

Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape

HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs

The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses.

Openings between defective endothelial cells explain tumor vessel leakiness

Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

A triple beta-spiral in the adenovirus fibre shaft reveals a new structural motif for a fibrous protein

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

Crystal structure of the receptor-binding domain of adenovirus type 5 fiber protein at 1.7 A resolution

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2290-2355

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10.3390/V2102290

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10

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2

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Stuart A Nicklin

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2010-10-13T00:00:00Z

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51711952

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21994621

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