Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates - Wikidata - wikimedia - TriplyDB

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

http://www.wikidata.org/entity/Q34362314

about

Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types The role of RNA interference (RNAi) in arbovirus-vector interactions Accessory Factors of Cytoplasmic Viral RNA Sensors Required for Antiviral Innate Immune Response Regulation of antiviral innate immune signaling by stress-induced RNA granules ADAR1, inosine and the immune sensing system: distinguishing self from non-self Sensors of Infection: Viral Nucleic Acid PRRs in Fish Interferon induction by RNA viruses and antagonism by viral pathogens Sensing viral RNAs by Dicer/RIG-I like ATPases across species Prion-like polymerization as a signaling mechanism RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling mRNA capping: biological functions and applications Innate immune recognition of DNA: A recent history International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease RIG-I in RNA virus recognition RIG-I-like receptor regulation in virus infection and immunity Interferons and viruses: an evolutionary arms race of molecular interactions LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling Influenza virus activation of the interferon system Viral evasion of intracellular DNA and RNA sensing Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.Interferon-Lambda: A Potent Regulator of Intestinal Viral Infections.Aicardi-Goutières syndrome and the type I interferonopathies.Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression RIG-I ATPase activity and discrimination of self-RNA versus non-self-RNA.Retroviral vectors elevate coexpressed protein levels in trans through cap-dependent translation.Potential role for snoRNAs in PKR activation during metabolic stress Hepatitis C Virus. Strategies to Evade Antiviral Responses Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon Induction Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5 MDA5-filament, dynamics and disease.Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response Biogenesis, delivery, and function of extracellular RNA.Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I.Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases Identification of 5-Methoxy-2-(Diformylmethylidene)-3,3-Dimethylindole as an Anti-Influenza A Virus Agent Structural Insights into mitochondrial antiviral signaling protein (MAVS)-tumor necrosis factor receptor-associated factor 6 (TRAF6) signaling.Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)Mismatches in the Influenza A Virus RNA Panhandle Prevent Retinoic Acid-Inducible Gene I (RIG-I) Sensing by Impairing RNA/RIG-I Complex Formation ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.

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Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

http://www.wikidata.org/entity/Q34362314

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@ast

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@en

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@nl

type

label

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@ast

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@en

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@nl

prefLabel

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@ast

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@en

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@nl

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Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

@en

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Annemarthe G Van der Veen

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Christine Schuberth

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Delphine Goubau

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Janos Ludwig

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Jason A Iskarpatyoti

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Marion Goldeck

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Safia Deddouche

http://www.w3.org/2001/XMLSchema#string

Terence S Dermody

http://www.w3.org/2001/XMLSchema#string

Thomas Zillinger

http://www.w3.org/2001/XMLSchema#string

Tsutomu Fujimura

http://www.w3.org/2001/XMLSchema#string

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Genome engineering using the CRISPR-Cas9 system

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.

Activation of MDA5 requires higher-order RNA structures generated during virus infection

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

Cytosolic sensing of viruses

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing)

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

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372-375

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scholarly article

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10.1038/NATURE13590

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7522

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514

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Winfried Barchet

Caetano Reis e Sousa

Gunther Hartmann

Andrea J Pruijssers

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2014-08-10T00:00:00Z

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264796133

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1048979894

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25119032

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4201573

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