The internal quaternary ammonium receptor site of Shaker potassium channels.
about
Episodic ataxia type-1 mutations in the hKv1.1 cytoplasmic pore region alter the gating properties of the channelVoltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domainsPhysical determinants of strong voltage sensitivity of K+ channel blockThe voltage-dependent gate in MthK potassium channels is located at the selectivity filterStructures of KcsA in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding SiteExpression in mammalian cells and electrophysiological characterization of two mutant Kv1.1 channels causing episodic ataxia type 1 (EA-1)Distinct mechanisms of block of Kv1.5 channels by tertiary and quaternary amine clofilium compounds.Mechanism underlying slow kinetics of the OFF gating current in Shaker potassium channel.Ionic blockade of the rat connexin40 gap junction channel by large tetraalkylammonium ionsThe pore-lining region of shaker voltage-gated potassium channels: comparison of beta-barrel and alpha-helix bundle modelsSodium channel selectivity filter regulates antiarrhythmic drug bindingA structural motif for the voltage-gated potassium channel pore.Shaker pore structure as predicted by annealed atomic simulation using symmetry and novel geometric restraintsContributions of a negatively charged residue in the hydrophobic domain of the IRK1 inwardly rectifying K+ channel to K(+)-selective permeation.The P-region and S6 of Kv3.1 contribute to the formation of the ion conduction pathwayMutational analysis of ion conduction and drug binding sites in the inner mouth of voltage-gated K+ channels.Hydrophobic mutations alter the movement of Mg2+ in the pore of voltage-gated potassium channels.Oxidation of an engineered pore cysteine locks a voltage-gated K+ channel in a nonconducting stateStereoselective block of a human cardiac potassium channel (Kv1.5) by bupivacaine enantiomers.Cooperative subunit interactions in C-type inactivation of K channels.Mutations in the K+ channel signature sequence.The multi-ion nature of the pore in Shaker K+ channels.Potassium secretion by vestibular dark cell epithelium demonstrated by vibrating probe.Side-chain accessibilities in the pore of a K+ channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis.A permanent ion binding site located between two gates of the Shaker K+ channel.Evidence for multiple open and inactivated states of the hKv1.5 delayed rectifierLocal movement in the S2 region of the voltage-gated potassium channel hKv2.1 studied using cysteine mutagenesis.Control of ion conduction in L-type Ca2+ channels by the concerted action of S5-6 regions.Rapid intracellular TEA block of the KcsA potassium channel.Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism.Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels.Tuning the tetraethylammonium sensitivity of potassium channel Kcv by subunit combination.What keeps Kv channels small? The molecular physiology of modesty.A mutation in segment IVS6 disrupts fast inactivation of sodium channelsCalcium ions open a selectivity filter gate during activation of the MthK potassium channelThe contribution of hydrophobic residues in the pore-forming region of the ryanodine receptor channel to block by large tetraalkylammonium cations and Shaker B inactivation peptides.Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate.State-dependent block of BK channels by synthesized shaker ball peptides.Probing the cavity of the slow inactivated conformation of shaker potassium channels.Unidirectional K+ fluxes through recombinant Shaker potassium channels expressed in single Xenopus oocytes.
P2860
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P2860
The internal quaternary ammonium receptor site of Shaker potassium channels.
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
The internal quaternary ammonium receptor site of Shaker potassium channels.
@ast
The internal quaternary ammonium receptor site of Shaker potassium channels.
@en
The internal quaternary ammonium receptor site of Shaker potassium channels.
@nl
type
label
The internal quaternary ammonium receptor site of Shaker potassium channels.
@ast
The internal quaternary ammonium receptor site of Shaker potassium channels.
@en
The internal quaternary ammonium receptor site of Shaker potassium channels.
@nl
prefLabel
The internal quaternary ammonium receptor site of Shaker potassium channels.
@ast
The internal quaternary ammonium receptor site of Shaker potassium channels.
@en
The internal quaternary ammonium receptor site of Shaker potassium channels.
@nl
P2093
P1433
P1476
The internal quaternary ammonium receptor site of Shaker potassium channels.
@en
P2093
P304
P356
10.1016/0896-6273(93)90340-W
P407
P577
1993-03-01T00:00:00Z