Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity.
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NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analysesDifferential ligand binding affinities of human estrogen receptor-α isoformsNew approaches to making the microenvironment of the female reproductive tract hostile to HIV.Estrogen receptor-beta agonist diarylpropionitrile: biological activities of R- and S-enantiomers on behavior and hormonal response to stress.The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors.The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells.Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.Estradiol increases mucus synthesis in bronchial epithelial cells.Dehydroepiandrosterone-induces miR-21 transcription in HepG2 cells through estrogen receptor β and androgen receptorIGF-1 gene expression is differentially regulated by estrogen receptors α and β in mouse endometrial stromal cells and ovarian granulosa cells.Activation of ERα is necessary for estradiol's anorexigenic effect in female rats.Estrogen receptor β ligands: recent advances and biomedical applications.Phenethyl pyridines with non-polar internal substituents as selective ligands for estrogen receptor beta.Administration of 17β-estradiol to ovariectomized obese female mice reverses obesity-hypertension through an ACE2-dependent mechanism.Male Sex is Associated with a Reduced Alveolar Epithelial Sodium TransportGenistein increases estrogen receptor beta expression in prostate cancer via reducing its promoter methylation.Mechanisms by Which 17β-Estradiol (E2) Suppress Neuronal cox-2 Gene Expression.Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide.Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of EndometriosisSynthesis and biological evaluation of two agents for imaging estrogen receptor β by positron emission tomography: challenges in PET imaging of a low abundance target.Androgen receptors, sex behavior, and aggression.Characterization of the weak estrogen receptor alpha agonistic activity of exemestane.Effects of Long-Term Treatment with Estradiol and Estrogen Receptor Subtype Agonists on Serotonergic Function in Ovariectomized RatsEstradiol antagonism of glucocorticoid-induced GILZ expression in human uterine epithelial cells and murine uterus.Estrogen receptor α antagonists mediate changes in CCL20 and CXCL1 secretions in the murine female reproductive tractEstrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β.Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression.Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors.Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer.Estrogen receptor-α and estrogen receptor-β in the uterine vascular endothelium during pregnancy: functional implications for regulating uterine blood flow.Src Inhibition with saracatinib reverses fulvestrant resistance in ER-positive ovarian cancer models in vitro and in vivoIdentification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial CellsEffects of 17β-estradiol and estrogen receptor antagonists on the proliferation of gastric cancer cell linesEstrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma-induced retinal pathology.Transgenic zebrafish reveal tissue-specific differences in estrogen signaling in response to environmental water samples.Role of oestrogen receptors in bladder cancer development.Proliferative Properties of 17β-aminoestrogens in MCF-7 Human Breast Cancer Cells.In vitro evaluation of a tetrahydroisoquinoline derivative as a steroid sulfatase inhibitor and a selective estrogen receptor modulator.4,5-Diaryl-3-aminopyrazole derivatives as analogs of Combretastatin A-4: synthesis and biological evaluation.Use of antagonists and morpholinos in loss-of-function analyses: estrogen receptor ESR2a mediates the effects of 17alpha-ethinylestradiol on primordial germ cell distribution in zebrafish.
P2860
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P2860
Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@ast
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@en
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@nl
type
label
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@ast
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@en
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@nl
prefLabel
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@ast
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@en
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@nl
P2093
P356
P1476
Pyrazolo[1,5-a]pyrimidines: es ...... ptor beta antagonist activity.
@en
P2093
Dennis R Compton
In Young Lee
John A Katzenellenbogen
Kathryn E Carlson
Natalie A Rebacz
Shubin Sheng
P304
P356
10.1021/JM049631K
P407
P577
2004-11-01T00:00:00Z