Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.
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Putative Role of Red Wine Polyphenols against Brain Pathology in Alzheimer's and Parkinson's DiseaseNeurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's diseaseTheoretical Approaches to Lentiviral Mediated Neurotrophin Delivery in Potential Treatments of Parkinson's DiseaseModulation of neurotrophic signaling pathways by polyphenolsRegulatory networks between neurotrophins and miRNAs in brain diseases and cancersNeurotrophins in the ventral tegmental area: Role in social stress, mood disorders and drug abuseWill the Requirement by the US FDA to Simultaneously Co-Develop Companion Diagnostics (CDx) Delay the Approval of Receptor Tyrosine Kinase Inhibitors for RTK-Rearranged (ROS1-, RET-, AXL-, PDGFR-α-, NTRK1-) Non-Small Cell Lung Cancer Globally?A novel antagonist of p75NTR reduces peripheral expansion and CNS trafficking of pro-inflammatory monocytes and spares function after traumatic brain injury.TRKing down an old oncogene in a new era of targeted therapySortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasionEffects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's DiseaseA small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injuryA BDNF loop-domain mimetic acutely reverses spontaneous apneas and respiratory abnormalities during behavioral arousal in a mouse model of Rett syndrome.Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice.A data-driven approach for evaluating multi-modal therapy in traumatic brain injury.A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.Dual-Component Gelatinous Peptide/Reactive Oligomer Formulations as Conduit Material and Luminal Filler for Peripheral Nerve Regeneration.Screening the role of pronociceptive molecules in a rodent model of endometriosis pain.Acute administration of the small-molecule p75(NTR) ligand does not prevent hippocampal neuron loss or development of spontaneous seizures after pilocarpine-induced status epilepticusA small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.Functional and structural specific roles of activity-driven BDNF within circuits formed by single spiny stellate neurons of the barrel cortex.BNN27, a 17-Spiroepoxy Steroid Derivative, Interacts With and Activates p75 Neurotrophin Receptor, Rescuing Cerebellar Granule Neurons from Apoptosis.Ligand-induced dynamics of neurotrophin receptors investigated by single-molecule imaging approaches.A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease.NGF and ProNGF: Regulation of neuronal and neoplastic responses through receptor signaling.Stress, trauma and PTSD: translational insights into the core synaptic circuitry and its modulation.BDNF modulates heart contraction force and long-term homeostasis through truncated TrkB.T1 receptor activationA novel natural product inspired scaffold with robust neurotrophic, neurogenic and neuroprotective actionMolecular changes in the medial prefrontal cortex and nucleus accumbens are associated with blocking the behavioral sensitization to cocaine.ERα Signaling Is Required for TrkB-Mediated Hippocampal Neuroprotection in Female Neonatal Mice after Hypoxic Ischemic Encephalopathy(1,2,3).Molecular Mechanisms Regulating LPS-Induced Inflammation in the Brain.Amitriptyline protects against TNF-α-induced atrophy and reduction in synaptic markers via a Trk-dependent mechanismAltered microRNA expression profiles in a rat model of spina bifida.Xtalk: a path-based approach for identifying crosstalk between signaling pathwaysThe Neurotrophic Factor Receptor p75 in the Rat Dorsolateral Striatum Drives Excessive Alcohol DrinkingA small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease.Airway smooth muscle in airway reactivity and remodeling: what have we learned?BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin.The Inorganic Side of NGF: Copper(II) and Zinc(II) Affect the NGF Mimicking Signaling of the N-Terminus Peptides Encompassing the Recognition Domain of TrkA Receptor.Sex differences in brain-derived neurotrophic factor signaling and functions.
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P2860
Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Small-molecule modulation of n ...... tment of neurological disease.
@ast
Small-molecule modulation of n ...... tment of neurological disease.
@en
Small-molecule modulation of n ...... tment of neurological disease.
@nl
type
label
Small-molecule modulation of n ...... tment of neurological disease.
@ast
Small-molecule modulation of n ...... tment of neurological disease.
@en
Small-molecule modulation of n ...... tment of neurological disease.
@nl
prefLabel
Small-molecule modulation of n ...... tment of neurological disease.
@ast
Small-molecule modulation of n ...... tment of neurological disease.
@en
Small-molecule modulation of n ...... tment of neurological disease.
@nl
P2860
P356
P1476
Small-molecule modulation of n ...... tment of neurological disease.
@en
P2093
Frank M Longo
Stephen M Massa
P2860
P2888
P304
P356
10.1038/NRD4024
P577
2013-07-01T00:00:00Z